8-氯-6-(三氟甲基)咪唑并[1,2-a]-吡啶-2-羧酸乙酯合成路线 （共 2 条）
反应条件
in ethanol T=20 - 80°C; 12 h;
参考文献
EXELIXIS, INC.; CANNE BANNEN, Lynne; CHAN, Diva Sze-ming; GU, Xiao-hui; MAC, Morrison, B.; NG, Stephanie; WANG, Tie-lin; WANG, Yong; XU, Wei
Patent: WO2010/65760 A1, 2010 ;
Location in patent: Page/Page column 102 ;
WO 2010/065760 A1
反应条件
1: With water; sodium hydroxide in methanol T=50°C; 1 h; 2: With acetic acid in water pH=4;
参考文献
EXELIXIS, INC.; CANNE BANNEN, Lynne; CHAN, Diva Sze-ming; GU, Xiao-hui; MAC, Morrison, B.; NG, Stephanie; WANG, Tie-lin; WANG, Yong; XU, Wei
Patent: WO2010/65760 A1, 2010 ;
Location in patent: Page/Page column 102 ;
WO 2010/065760 A1
