2-(3-氯苯氧基)乙酰胺合成路线 （共 7 条）
反应条件
potassium carbonate in acetone T=70°C;
参考文献
SUNSHINE LAKE PHARMA CO., LTD.; ZHANG, Yingjun; ZHANG, Jiancun; WANG, Xiaojun; LIN, Runfeng; CAO, Shengtian; WANG, Zhaohe; LI, Jing
Patent: WO2014/12360 A1, 2014 ;
Location in patent: Paragraph 00529 ;
反应条件
ammonia in water; toluene T=0 - 5°C; 1.5 h;
参考文献
Li, Ting; Liu, Guyue; Li, Hongcai; Yang, Xinmei; Jing, Yongkui; Zhao, Guisen
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 7 p. 2316 - 2322
反应条件
1: sodium hydroxide / 100 °C 2: thionyl chloride / 4 h / 80 °C 3: ammonia / water; toluene / 1.5 h / 0 - 5 °C View Scheme
参考文献
Li, Ting; Liu, Guyue; Li, Hongcai; Yang, Xinmei; Jing, Yongkui; Zhao, Guisen
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 7 p. 2316 - 2322
反应条件
1: thionyl chloride / 4 h / 80 °C 2: ammonia / water; toluene / 1.5 h / 0 - 5 °C View Scheme
参考文献
Li, Ting; Liu, Guyue; Li, Hongcai; Yang, Xinmei; Jing, Yongkui; Zhao, Guisen
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 7 p. 2316 - 2322
反应条件
sodium hydroxide; isopropyl alcohol
参考文献
Leaper; Bishop
Bot. Gaz., 1951 , vol. 112, p. 250,252
参考文献
Leaper; Bishop
Bot. Gaz., 1951 , vol. 112, p. 250,252
反应条件
tetraphosphorus decasulfide in tetrahydrofuran T=50°C; 1.5 h;
参考文献
Li, Ting; Liu, Guyue; Li, Hongcai; Yang, Xinmei; Jing, Yongkui; Zhao, Guisen
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 7 p. 2316 - 2322
