1-(2-甲氧苯基)哌嗪合成路线

参考文献

Neurogen Corporation, Corporation of the State of Delaware
Patent: US2003/18025 A1, 2003 ;
US 20030018025 A1

参考文献

Pike, Victor W.; McCarron, Julie A.; Hume, Susan P.; Ashworth, Sharon; Opacka-Juffry, Jolanta; et al.
Medicinal Chemistry Research, 1995 , vol. 5, # 2/3 p. 208 - 227

35386-24-41-(2-甲氧苯基)哌嗪

146714-63-84-(2-甲氧基苯基)-N-2-吡啶基-1-哌嗪乙酰胺

参考文献

O'Connor, Naphtali A.; Paisner, David A.; Huryn, Donna; Shea, Kenneth J.
Journal of the American Chemical Society, 2007 , vol. 129, # 6 p. 1680 - 1689

35386-24-41-(2-甲氧苯基)哌嗪

219125-59-42-[4-(2-甲氧基苯基)哌嗪]乙烷硫代酰胺

参考文献

Perrone; Berardi; Colabufo; Leopoldo; Tortorella
Journal of Medicinal Chemistry, 1998 , vol. 41, # 24 p. 4903 - 4909

35386-24-41-(2-甲氧苯基)哌嗪+

100-44-7苄基氯

21091-60-12-(4-苄基-1-哌嗪)甲氧基苯

参考文献

Sukalovic, Vladimir; Zlatovic, Mario; Andric, Deana; Roglic, Goran; Kostic-Rajacic, Sladjana; Soskic, Vukic
Arzneimittel-Forschung/Drug Research, 2005 , vol. 55, # 3 p. 145 - 152

35386-24-41-(2-甲氧苯基)哌嗪+

100-39-0溴化苄

21091-60-12-(4-苄基-1-哌嗪)甲氧基苯

参考文献

Mewshaw, Richard E.; Husbands, Morris; Gildersleeve, Elizabeth S.; Webb, Michael B.; Shi, Xiaojie; Mazandarani, Hossein; Cockett, Mark I.; Ochalski, Rafal; Brennan, Julie A.; Abou-Gharbia, Magid; Marquis, Karen; McGaughey, Georgia B.; Coupet, Joseph; Andree, Terrance H.
Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 3 p. 295 - 300

5394-18-3N-(4-溴丁基)邻苯二甲酰亚胺+

35386-24-41-(2-甲氧苯基)哌嗪

21103-33-34-4-(2-甲氧基-苯基)-哌嗪-1-基-丁基胺

参考文献

Neurogen Corporation
Patent: US5703237 A1, 1997 ;
US 5703237 A

35386-24-41-(2-甲氧苯基)哌嗪

21103-33-34-4-(2-甲氧基-苯基)-哌嗪-1-基-丁基胺

参考文献

Chu, Wenhua; Tu, Zhude; McElveen, Elizabeth; Xu, Jinbin; Taylor, Michelle; Luedtke, Robert R.; MacH, Robert H.
Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 1 p. 77 - 87

35386-24-41-(2-甲氧苯基)哌嗪+

79-04-9一氯代乙酰氯

21057-39-61-(氯乙酰基)-4-(2-甲氧基苯基)哌嗪盐酸盐

参考文献

Abou El-Ella, Dalal A.; Hussein, Mohammed M.; Serya, Rabah A.T.; Abdel Naby, Rana M.; Al-Abd, Ahmed M.; Saleh, Dalia O.; El-Eraky, Wafaa I.; Abouzid, Khaled A.M.
Bioorganic Chemistry, 2014 , vol. 54, p. 21 - 30

35386-24-41-(2-甲氧苯基)哌嗪+

109-70-61-溴-3-氯丙烷

参考文献

Caliendo, Giuseppe; Fiorino, Ferdinando; Grieco, Paolo; Perissutti, Elisa; Santagada, Vincenzo; Severino, Beatrice; Bruni, Giancarlo; Romeo, Maria Rosaria
Bioorganic and Medicinal Chemistry, 2000 , vol. 8, # 3 p. 533 - 538