2,2,2-三氟乙酰胺合成路线 （共 158 条）
参考文献
Arbuzov,B.A. et al.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1977 , vol. 26, p. 348 - 354
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1977 , vol. 26, p. 387 - 393
反应条件
potassium phosphate; tris-(dibenzylideneacetone)dipalladium(0) in tert-butyl alcohol
T=90°C; 4 h;
参考文献
Ikawa, Takashi; Barder, Timothy E.; Biscoe, Mark R.; Buchwald, Stephen L.
Journal of the American Chemical Society, 2007 , vol. 129, # 43 p. 13001 - 13007
反应条件
potassium carbonate; N-methyl-2-(methylamino)ethylamine; copper(l) iodide in 1,4-dioxane
T=75°C;
参考文献
Tao, Chuan-Zhou; Li, Juan; Fu, Yao; Liu, Lei; Guo, Qing-Xiang
Tetrahedron Letters, 2008 , vol. 49, # 1 p. 70 - 75
反应条件
hydrogenchloride; potassium cyanide in tetrahydrofuran; methanol; water
参考文献
Naleway, John J.; Jiang, Ying; Link-Cole, Ryan
Patent: US2013/150254 A1, 2013 ;
Location in patent: Page/Page column ;
反应条件
sodium hydride
1.) DMF, 20 deg C, 1 h, 2.) 80 deg C, 18 h; Yield given. Multistep reaction;
参考文献
Harland, Philip A.; Hodge, Philip; Maughan, Wilfrid; Wildsmith, Eric
Synthesis, 1984 , # 11 p. 941 - 943
参考文献
Meen; Wright
Journal of Organic Chemistry, 1954 , vol. 19, p. 391,399
反应条件
potassium phosphate; N-methyl-2-(methylamino)ethylamine; copper(l) iodide in N,N-dimethyl-formamide
T=45°C;
参考文献
Tao, Chuan-Zhou; Li, Juan; Fu, Yao; Liu, Lei; Guo, Qing-Xiang
Tetrahedron Letters, 2008 , vol. 49, # 1 p. 70 - 75
反应条件
sodium hypoiodite
At 0°C then at boiling point for 0.25 h.;
参考文献
Barr, D. A.; Haszeldine, R. N.
Journal of the Chemical Society, 1957 , p. 30 - 39
