1: palladium diacetate; copper diacetate; potassium carbonate / N,N-dimethyl-formamide / 15 h / 80 °C / |Inert atmosphere 2: sodium hydroxide / tetrahydrofuran / 2 h / 20 °C 3: sodium hydroxide / water; ethanol / 15 h / 80 °C 4: thionyl chloride / dichloromethane / 1 h / 20 °C 5: dichloromethane / 2 h / -20 - 20 °C 6: [bis(acetoxy)iodo]benzene / 1,2-dichloro-ethane / 1 h / 20 °C 7: sodium hydride / N,N-dimethyl-formamide; mineral oil / 1 h / 120 °C View Scheme

sulfuric acid in tetrahydrofuran

diphenylether

copper diacetate; palladium diacetate; potassium carbonate in N,N-dimethyl-formamide T=180°C; 1 h; Microwave irradiationInert atmosphere;

silver carbonate T=110°C; 24 h; Inert atmosphere;

palladium diacetate; silver carbonate T=110°C; 24 h; Inert atmosphere;

1: palladium diacetate; copper diacetate; potassium carbonate / N,N-dimethyl-formamide / 15 h / 80 °C / |Inert atmosphere 2: sodium hydroxide / tetrahydrofuran / 2 h / 20 °C 3: sodium hydroxide / water; ethanol / 15 h / 80 °C View Scheme

silver carbonate T=110°C; 24 h; Inert atmosphere;