3-(4-氨基苯基)丙酸甲酯合成路线 （共 19 条）
参考文献
Skinner et al.
Journal of the American Chemical Society, 1959 , vol. 81, p. 4639,4641
反应条件
1: H2 / Pd View Scheme
参考文献
CHIESI FARMACEUTICI S.P.A.; ARMANI, Elisabetta; AMARI, Gabriele; CAPALDI, Carmelida; ESPOSITO, Oriana; PERETTO, Ilaria
Patent: WO2013/45280 A1, 2013 ;
反应条件
1: nitration agent 2: H2 / Pd View Scheme
参考文献
Mertens, J.; Boumon, R.; Steegmans, P.
Journal of Labelled Compounds and Radiopharmaceuticals, 2001 , vol. 44, p. S951 - S953
反应条件
1: triethylamine; Pd(PPh3)2Cl2; lithium chloride / N,N-dimethyl-formamide / 3 h / 130 °C / |Inert atmosphere; |Microwave irradiation; |Sealed tube 2: hydrogen; palladium 10 on activated carbon / methanol / 3 h / 20 °C 3: trifluoroacetic acid / dichloromethane / 3 h / 0 - 20 °C / |Inert atmosphere View Scheme
参考文献
Kabro, Anzhelika; Lachance, Hugo; Marcoux-Archambault, Iris; Perrier, Valerie; Dore, Vicky; Gros, Christina; Masson, Veronique; Gregoire, Jean-Marc; Ausseil, Frederic; Cheishvili, David; Laulan, Nathalie Bibens; St-Pierre, Yves; Szyf, Moshe; Arimondo, Paola B.; Gagnon, Alexandre
MedChemComm, 2013 , vol. 4, # 12 p. 1562 - 1570
反应条件
1: hydrogen; palladium 10 on activated carbon / methanol / 3 h / 20 °C 2: trifluoroacetic acid / dichloromethane / 3 h / 0 - 20 °C / |Inert atmosphere View Scheme
参考文献
Kabro, Anzhelika; Lachance, Hugo; Marcoux-Archambault, Iris; Perrier, Valerie; Dore, Vicky; Gros, Christina; Masson, Veronique; Gregoire, Jean-Marc; Ausseil, Frederic; Cheishvili, David; Laulan, Nathalie Bibens; St-Pierre, Yves; Szyf, Moshe; Arimondo, Paola B.; Gagnon, Alexandre
MedChemComm, 2013 , vol. 4, # 12 p. 1562 - 1570
反应条件
1: triethylamine / isopropyl alcohol / 2 h / 20 °C / |Inert atmosphere 2: triethylamine; Pd(PPh3)2Cl2; lithium chloride / N,N-dimethyl-formamide / 3 h / 130 °C / |Inert atmosphere; |Microwave irradiation; |Sealed tube 3: hydrogen; palladium 10 on activated carbon / methanol / 3 h / 20 °C 4: trifluoroacetic acid / dichloromethane / 3 h / 0 - 20 °C / |Inert atmosphere View Scheme
参考文献
Kabro, Anzhelika; Lachance, Hugo; Marcoux-Archambault, Iris; Perrier, Valerie; Dore, Vicky; Gros, Christina; Masson, Veronique; Gregoire, Jean-Marc; Ausseil, Frederic; Cheishvili, David; Laulan, Nathalie Bibens; St-Pierre, Yves; Szyf, Moshe; Arimondo, Paola B.; Gagnon, Alexandre
MedChemComm, 2013 , vol. 4, # 12 p. 1562 - 1570
参考文献
Radeglia, R.; Spassov, S. L.; Stefanova, R.; Simova, S. D.
Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, 1980 , vol. 35, # 7 p. 934 - 936
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=0 - 20°C;
参考文献
DR. REDDY'S LABORATORIES LIMITED
Patent: US2003/229083 A1, 2003 ;
Location in patent: Page 24 ;
反应条件
2,6-dimethylpyridine; n-tetradecanoic acid; copper diacetate in toluene
T=25°C; 24 h;
参考文献
Hardouin, Christophe; Kelso, Michael J.; Romero, F. Anthony; Rayl, Thomas J.; Leung, Donmienne; Hwang, Inkyu; Cravatt, Benjamin F.; Boger, Dale L.
Journal of Medicinal Chemistry, 2007 , vol. 50, # 14 p. 3359 - 3368
