3-甲氧基-4-硝基苯甲醛合成路线 （共 5 条）
反应条件
dipyridinium dichromate in dichloromethane T=10 - 20°C; 3 h;
参考文献
NEUROPORE THERAPIES, INC.; WRASIDLO, Wolfgang
Patent: WO2013/148365 A1, 2013 ;
Location in patent: Paragraph 0095 ;
反应条件
diisobutylaluminium hydride in dichloromethane T=-78°C; Inert atmosphere;
参考文献
Brandt, Gary E. L.; Blagg, Brian S. J.
ACS Medicinal Chemistry Letters, 2011 , vol. 2, # 10 p. 735 - 740
反应条件
1: HMPA / 25 °C 2: BH3 / tetrahydrofuran / 16 h / 0 - 25 °C 3: PDC; mol. sieves 4A / CH2Cl2 / 5 h / 25 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 47, # 11 p. 2897 - 2905
反应条件
1: BH3 / tetrahydrofuran / 16 h / 0 - 25 °C 2: PDC; mol. sieves 4A / CH2Cl2 / 5 h / 25 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 47, # 11 p. 2897 - 2905
反应条件
1.1: lithium / 0 °C / Inert atmosphere 1.2: Reflux; Inert atmosphere 2.1: diisobutylaluminium hydride / dichloromethane / -78 °C / Inert atmosphere View Scheme
参考文献
ACS Medicinal Chemistry Letters, , vol. 2, # 10 p. 735 - 740
