5-氨基-2,4,6-三碘间苯二甲酸合成路线 （共 9 条）
反应条件
sulfuric acid; iodine; iodic acid in water T=72°C; pH=1; 6.2 h; Product distribution / selectivity;
参考文献
EP2243767 A1, ;
Page/Page column 8 ;
反应条件
iodine cloride in water
反应条件
pyridine; thionyl chloride in 1,2-dichloro-ethane T=70 - 85°C; 8.5 h;
参考文献
GE HEALTHCARE AS
Patent: WO2008/123779 A1, 2008 ;
Location in patent: Page/Page column 12; 14; 15 ;
参考文献
Mitsui Toatsu Chemicals, Inc.
Patent: US5750779 A1, 1998 ;
参考文献
Mitsui Toatsu Chemicals, Inc.
Patent: US5750779 A1, 1998 ;
反应条件
1: isobutyramide / 22 h / 20 - 50 °C 2: phosphorus pentachloride / isobutyramide / 6 h / 40 °C 3: triethylamine / isobutyramide / 6 h / 50 °C 4: sodium hydroxide; water / 40 °C / pH ~ 11 View Scheme
反应条件
1: 92 percent / thionyl chloride 2: N,N-dimethyl-acetamide / 16 h / Ambient temperature View Scheme
参考文献
Pillai, K. M. R.; Diamantidis, G.; Duncan, L.; Ranganathan, R. S.
Journal of Organic Chemistry, 1994 , vol. 59, # 6 p. 1344 - 1350
反应条件
1: 92 percent / thionyl chloride 2: N,N-dimethyl-acetamide / 16 h / Ambient temperature 3: pyridine / 6 h / Ambient temperature View Scheme
参考文献
Pillai, K. M. R.; Diamantidis, G.; Duncan, L.; Ranganathan, R. S.
Journal of Organic Chemistry, 1994 , vol. 59, # 6 p. 1344 - 1350
反应条件
sulfuric acid in water
T=40 - 50°C; 2 h;
参考文献
GE HEALTHCARE AS
Patent: WO2009/60021 A1, 2009 ;
Location in patent: Page/Page column 17 ;
