2,2,3,3,4,4,5,5-八氟-1-戊醇合成路线 （共 86 条）
反应条件
tetrachloromethane; ethanesulfonic acid
参考文献
Faurote et al.
Industrial and Engineering Chemistry, 1956 , vol. 48, p. 445,447
参考文献
Minnesota Mining and Manufacturing Company
Patent: US5157159 A1, 1992 ;
反应条件
tetra-(n-butyl)ammonium iodide
T=90 - 140°C; 90 h; Yields of byproduct given;
参考文献
Heilmann, S. M.; Drtina, G. J.; Janulis, E. P.; Krepski, L. R.; Rasmussen, J. K.; et al.
Journal of Fluorine Chemistry, 1992 , vol. 59, # 3 p. 387 - 396
反应条件
1: 1) NaH / 1) THF, T>10 deg C, 30 min, 2a) THF, T>5 deg C, 1h, 2b) RT, overnight
2: 77 percent / LiAlH4 / diethyl ether / 3 h / Ambient temperature
View Scheme
参考文献
Chiang, Y. H.; Ames, A. E.; Gaudiana, R. A.; Adams, T. G.
Molecular Crystals and Liquid Crystals (1969-1991), 1991 , vol. 208, p. 85 - 98
反应条件
1: With titanium tetrachloride
Inert atmosphere;
2: With zinc in diethylene glycol dimethyl ether
T=90°C; 9 h; Cooling with ice;
参考文献
E. I. DU PONT DE NEMOURS AND COMPANY; STEPANOV, Andrei, Aleksandrovich; CHERSTKOV, Victor, Filippovich; NAPPA, Mario, Joseph
Patent: WO2011/90734 A1, 2011 ;
Location in patent: Page/Page column 6-7 ;
反应条件
in 1,2-dichloro-ethane
T=35 - 37°C;
参考文献
Kuplennik, Z.I.; Belaya, Zh. N.; Pinchuk, A. M.
J. Gen. Chem. USSR (Engl. Transl.), 1981 , vol. 51, # 12 p. 2711 - 2715,2339 - 2343
