4-(异丙氨基)-3-硝基苯甲腈合成路线 （共 4 条）
反应条件
in acetonitrile T=120°C; 0.333333 h; microwave irradiation;
参考文献
Semple, Graeme; Skinner, Philip J.; Cherrier, Martin C.; Webb, Peter J.; Sage, Carleton R.; Tamura, Susan Y.; Chen, Ruoping; Richman, Jeremy G.; Connolly, Daniel T.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 4 p. 1227 - 1230
反应条件
in N,N-dimethyl-formamide T=35°C; 1 h;
参考文献
Goeker, Hakan; Tuncbilek, Meral; Suezen, Sibel; Kus, Canan; Altanlar, Nurten
Archiv der Pharmazie, 2001 , vol. 334, # 5 p. 148 - 152
反应条件
hydrogen; palladium on activated charcoal in ethanol T=20°C; P=2068.59 Torr;
参考文献
Goeker, Hakan; Kus, Canan; Boykin, David W.; Yildiz, Sulhiye; Altanlar, Nurten
Bioorganic and Medicinal Chemistry, 2002 , vol. 10, # 8 p. 2589 - 2596
反应条件
1: H2 / Pd/C / ethyl acetate / 2 h / 20 °C
2: AcOH; NaNO2 / 18 h / 20 °C
View Scheme
参考文献
Semple, Graeme; Skinner, Philip J.; Cherrier, Martin C.; Webb, Peter J.; Sage, Carleton R.; Tamura, Susan Y.; Chen, Ruoping; Richman, Jeremy G.; Connolly, Daniel T.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 4 p. 1227 - 1230
