2,4,6-三羟基二苯甲酮合成路线 （共 23 条）
反应条件
1: 1,3,5-trishydroxybenzene With AlCl3, aluminium chloride in nitrobenzene T=20°C; Friedel-Crafts Acylation; 0.5 h; 2: benzoyl chloride in nitrobenzene T=65°C; 2 h;
参考文献
Pepper, Henry P.; Tulip, Stephen J.; Nakano, Yuji; George, Jonathan H.
Journal of Organic Chemistry, 2014 , vol. 79, # 6 p. 2564 - 2573
反应条件
boron tribromide in dichloromethane T=-78 - 20°C;
参考文献
Mondal, Mukulesh; Puranik, Vedavati G.; Argade, Narshinha P.
Journal of Organic Chemistry, 2007 , vol. 72, # 6 p. 2068 - 2076
反应条件
sodium hydroxide T=-5°C;
参考文献
Harris,T.M.; Carney,R.L.
Journal of the American Chemical Society, 1967 , vol. 89, p. 6734 - 6741
反应条件
1: diethyl ether 2: aq. NaOH / -5 °C View Scheme
参考文献
Harris,T.M.; Carney,R.L.
Journal of the American Chemical Society, 1967 , vol. 89, p. 6734 - 6741
反应条件
1: ZnCl2; HCl / diethyl ether 2: H2O / 1.5 h / Heating View Scheme
参考文献
Phadke; Shah
Journal of the Indian Chemical Society, 1950 , vol. 27, p. 349,353
反应条件
1: 96 percent / AlCl3 / CH2Cl2 / 12 h / 0 - 20 °C 2: 92 percent / boron tribromide / CH2Cl2 / -78 - 20 °C View Scheme
参考文献
Thevenin, Marion; Mouray, Elisabeth; Grellier, Philippe; Dubois, Joelle
European Journal of Organic Chemistry, 2014 , vol. 2014, # 14 p. 2986 - 2992
反应条件
boron trifluoride diethyl etherate in benzene crossover Friess rearrangement; 3 h; Heating;
参考文献
Khanna, R. N.; Singh, K. P.; Sharma, Jyotsana
Organic Preparations and Procedures International, 1992 , vol. 24, # 6 p. 687 - 690
反应条件
1: 96 percent / AlCl3 / CH2Cl2 / 12 h / 0 - 20 °C 2: 92 percent / boron tribromide / CH2Cl2 / -78 - 20 °C View Scheme
参考文献
Pathak, V. P.; Khanna, R. N.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. 21, # 3 p. 253 - 254
反应条件
boron trifluoride diethyl etherate in benzene cross Fries reaction; 0.5 h; microwave irradiation;
参考文献
Thapliyal; Aggarwal
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2000 , vol. 39, # 9 p. 706 - 708
反应条件
zinc(II) chloride; trichlorophosphate T=70°C; Friedel-Crafts reaction; 2.5 h;
参考文献
Wu, Jianlong; Hu, Xuesen; Ma, Lin
Journal of Enzyme Inhibition and Medicinal Chemistry, 2011 , vol. 26, # 3 p. 449 - 452
