3-氯-1,1-二乙氧基丙烷合成路线 （共 57 条）
参考文献
Mikolajczyk, M.; Grzejszczak, S.; Midura, W.; Zatorski, A.
Phosphorus and Sulfur and the Related Elements, 1983 , vol. 18, p. 175 - 178
反应条件
in N,N-dimethyl-formamide
参考文献
Normant,H.; Sturtz,G.
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1961 , vol. 253, p. 2366 - 2368
反应条件
water; naphthalenyllithium 1.) THF, -78 deg C, 6 h, 2.) 20 deg C, 2 h; Yield given. Multistep reaction;
参考文献
Barluenga, Jose; Rubiera, Covadonga; Fernandez, Jose R.; Yus, Miguel
Journal of the Chemical Society, Chemical Communications, 1987 , # 6 p. 425 - 426
反应条件
2: water; HClO 3: potash View Scheme
参考文献
Wohl
Chemische Berichte, 1898 , vol. 31, p. 1799
反应条件
1: 3-chloro-propionaldehyde diethyl acetal With lithium; 4,4'-di-tert-butylbiphenyl in tetrahydrofuran T=-78°C; 1 h; 2: With zinc dibromide in tetrahydrofuran T=-78 - 20°C; 3: 1-bromo-2-chloro-benzene With Pd(OAc)2(PPh3)2 in tetrahydrofuran T=70°C; Negishi cross-coupling reaction; 24 h; Further stages.;
参考文献
Yus, Miguel; Gomis, Joaquin
European Journal of Organic Chemistry, 2002 , # 12 p. 1989 - 1995
参考文献
Barger; Coyne
Biochemical Journal, 1928 , vol. 22, p. 1423
参考文献
Yamanishi; Obata
Nippon Nogei Kagaku Kaishi, 1953 , vol. 27, p. 657
Chem.Abstr., 1955 , p. 2300
参考文献
Barger; Coyne
Biochemical Journal, 1928 , vol. 22, p. 1423
参考文献
Back,W.; Mutschler,E.
Archiv der Pharmazie und Berichte der Deutschen Pharmazeutischen Gesellschaft, 1967 , vol. 300, p. 955 - 963
反应条件
(i) NaH, benzene, DMF, (ii) /BRN= 1698609/, KI; Multistep reaction;
参考文献
Brenner,J.E.
Journal of Organic Chemistry, 1961 , vol. 26, p. 22 - 27
