1-甲基-2-苯基吲哚合成路线 (共 124 条)
反应条件
2,6-di-tert-butyl-pyridine; copper(II) bis(trifluoromethanesulfonate) in dichloromethane T=20°C; 26 h;
参考文献
Phipps, Robert J.; Grimster, Neil P.; Gaunt, Matthew J.
Journal of the American Chemical Society, 2008 , vol. 130, # 26 p. 8172 - 8174
反应条件
potassium fluoride; 2,2,6,6-tetramethyl-1-piperidinyloxy, free radical; palladium diacetate in propionic acid T=20°C; 1 h;
参考文献
Angewandte Chemie, International Edition, , vol. 48, # 23 p. 4235 - 4238
反应条件
copper(l) iodide; triethylamine; bis-triphenylphosphine-palladium(II) chloride in N,N-dimethyl-formamide T=20°C; Sonogashira coupling; 8 h;
参考文献
Oskooie, Hossien A.; Heravi, Majid M.; Behbahani, Farahnaz K.
Molecules, 2007 , vol. 12, # 7 p. 1438 - 1446
反应条件
copper(l) iodide; triethylamine; bis-triphenylphosphine-palladium(II) chloride in N,N-dimethyl-formamide T=20°C; Sonogashira coupling; 8 h;
参考文献
Oskooie, Hossien A.; Heravi, Majid M.; Behbahani, Farahnaz K.
Molecules, 2007 , vol. 12, # 7 p. 1438 - 1446
反应条件
tetrabutyl ammonium fluoride; palladium diacetate; acetic acid; silver(l) oxide in tetrahydrofuran; ethanol T=20°C; Inert atmosphere; regioselective reaction;
参考文献
Liang, Zunjun; Yao, Bangben; Zhang, Yuhong
Organic Letters, 2010 , vol. 12, # 14 p. 3185 - 3187
反应条件
tetrabutyl ammonium fluoride; palladium diacetate; acetic acid; silver(l) oxide in tetrahydrofuran; ethanol T=20°C; Inert atmosphere; regioselective reaction;
参考文献
Liang, Zunjun; Yao, Bangben; Zhang, Yuhong
Organic Letters, 2010 , vol. 12, # 14 p. 3185 - 3187
反应条件
tetrabutyl ammonium fluoride; palladium diacetate; acetic acid; silver(l) oxide in tetrahydrofuran; ethanol T=20°C; Inert atmosphere; regioselective reaction;
参考文献
Liang, Zunjun; Yao, Bangben; Zhang, Yuhong
Organic Letters, 2010 , vol. 12, # 14 p. 3185 - 3187
反应条件
1: With [(η5-cyclopentadienyl)2Ti(η2-Me3SiC2SiMe3)] in toluene T=100°C; 24 h; 2: With zinc(II) chloride in toluene T=100°C; 24 h;
参考文献
Chemistry - A European Journal, , vol. 10, # 10 p. 2409 - 2420
反应条件
1: [bis(acetoxy)iodo]benzene; 3,4,5-trimethoxyphenylboronic acid With palladium diacetate; acetic acid T=25°C; 0.25 h; 2: 1-methyl-1H-indole With acetic acid T=25°C; 15 h;
参考文献
Deprez, Nicholas R.; Kalyani, Dipannita; Krause, Andrew; Sanford, Melanie S.
Journal of the American Chemical Society, 2006 , vol. 128, # 15 p. 4972 - 4973
反应条件
silver nitrate in acetonitrile T=80°C; 8 h; Reagent/catalystTemperatureSolventTime;
参考文献
Yang, Lei; Ma, Yuanhong; Song, Feijie; You, Jingsong
Chemical Communications, 2014 , vol. 50, # 23 p. 3024 - 3026