1,2-二苯基-1-(4-羟基苯基)乙醇合成路线 (共 3 条)
反应条件
1: in tetrahydrofuran T=0 - 20°C; Grignard reaction; 24 h; Inert atmosphere; 2: With ammonium chloride in tetrahydrofuran Saturated solution;
参考文献
Abualhasan, Murad N.; Good, James A.D.; Wittayanarakul, Kitiyaporn; Anthony, Nahoum G.; Berretta, Giacomo; Rath, Oliver; Kozielski, Frank; Sutcliffe, Oliver B.; MacKay, Simon P.
European Journal of Medicinal Chemistry, 2012 , vol. 54, p. 483 - 498
反应条件
1: benzyl bromide With magnesium in tetrahydrofuran 1.33333 h; Heating; 2: 4-hydroxy-benzophenone in tetrahydrofuran T=20°C; 1.08333 h;
参考文献
Da Costa, Goncalo Gamboa; Marques, M. Matilde; Beland, Frederick A.; Freeman, James P.; Churchwell, Mona I.; Doerge, Daniel R.
Chemical Research in Toxicology, 2003 , vol. 16, # 3 p. 357 - 366
反应条件
bromine in tetrachloromethane
T=20°C; 1.08333 h;
参考文献
Da Costa, Goncalo Gamboa; Marques, M. Matilde; Beland, Frederick A.; Freeman, James P.; Churchwell, Mona I.; Doerge, Daniel R.
Chemical Research in Toxicology, 2003 , vol. 16, # 3 p. 357 - 366