(2R)-2-叠氮基-3-羟基-2-甲基-丙酸甲酯合成路线 （共 6 条）
反应条件
sodium azide in N,N-dimethyl-formamide T=50°C; 48 h;
参考文献
Avenoza, Alberto; Cativiela, Carlos; Corzana, Francisco; Peregrina, Jesus M.; Sucunza, David; Zurbano, Maria M.
Tetrahedron Asymmetry, 2001 , vol. 12, # 6 p. 949 - 957
反应条件
1: With sodium azide in N,N-dimethyl-formamide T=50°C; 48 h; 2: With sulfuric acid in water T=20°C; 48 h;
参考文献
Journal of Organic Chemistry, , vol. 68, # 11 p. 4506 - 4513
反应条件
1: thionyl chloride / CCl4 / Heating 2: sodium azide / dimethylformamide / 48 h / 50 °C View Scheme
参考文献
Organic Letters, , vol. 5, # 7 p. 1035 - 1037
反应条件
1.1: 92 percent / SOCl2 / CCl4 / 4 h / Heating 2.1: 86 percent / NaIO4; RuCl3 / acetonitrile; CCl4; H2O / 7 h / 40 °C 3.1: NaN3 / dimethylformamide / 48 h / 50 °C 3.2: H2SO4 / H2O / 48 h / 20 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 68, # 11 p. 4506 - 4513
反应条件
1.1: 86 percent / NaIO4; RuCl3 / acetonitrile; CCl4; H2O / 7 h / 40 °C 2.1: NaN3 / dimethylformamide / 48 h / 50 °C 2.2: H2SO4 / H2O / 48 h / 20 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 68, # 11 p. 4506 - 4513
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran
参考文献
Tetrahedron, , vol. 62, # 39 p. 9268 - 9279
