(2-氨基-苯基)-乙酸甲酯合成路线 （共 9 条）
反应条件
hydrogen; 10 percent Pd/C contd. 50percent water in ethyl acetate T=20°C; atmospheric pressure;
参考文献
Katayama, Seiji; Ae, Nobuyuki; Kodo, Toru; Masumoto, Shuji; Hourai, Shinji; Tamamura, Chika; Tanaka, Hiroyasu; Nagata, Ryu
Journal of Medicinal Chemistry, 2003 , vol. 46, # 5 p. 691 - 701
反应条件
1: H2SO4 / Heating 2: H2 / Pd-C / methanol View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 13, # 14 p. 4396 - 4401
反应条件
hydrogen; palladium on activated charcoal in ethyl acetate T=0°C; P=735.5 Torr; 4 h; Title compound not separated from byproducts;
参考文献
, vol. 1985, # 7 p. 1398 - 1412
反应条件
water in dichloromethane T=20°C; 0.5 h;
参考文献
Oezcan, Sevil; Balci, Metin
Tetrahedron, 2008 , vol. 64, # 23 p. 5531 - 5540
反应条件
thionyl chloride T=0 - 20°C;
参考文献
US2008/312231 A1, ;
Page/Page column 37 ;
US 20080312231 A1
反应条件
0.333333 h; Heatingunder reduced pressure;
参考文献
Fife, Thomas H.; Duddy, Neil W.
Journal of the American Chemical Society, 1983 , vol. 105, # 1 p. 74 - 79
参考文献
Neber
Chemische Berichte, 1922 , vol. 55, p. 839
反应条件
1: potassium carbonate / N,N-dimethyl-formamide / 20 °C
2: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran / 0 - 20 °C
View Scheme
参考文献
CROWN BIOSCIENCE INC. (TAICANG); ZHANG, Deyi; ZHANG, Ruihao; ZHONG, Boyu; SHIH, Chuan
Patent: WO2014/418 A1, 2014 ;
反应条件
sodium tris(acetoxy)borohydride; sodium hydrogencarbonate; acetic acid in dichloromethane
参考文献
Butler, Christopher R.; Cai, Hui; Edwards, James P.; Grice, Cheryl A.; Gu, Yin; Gustin, Darin J.; Karlsson, Lars; Khatuya, Haripada; Meduna, Steven P.; Pio, Barbara A.; Sehon, Clark A.; Sun, Siquan; Tays, Kevin L.; Thurmond, Robin L.; Wei, Jianmei
Patent: US2005/101587 A9, 2005 ;
