2,2,4-三甲基-6-苯基-1H-喹啉合成路线 （共 3 条）
反应条件
in N-(6,7-dibutoxy-4-methyl-2-quinazolinyl)guanidine
参考文献
Forray, Carlos C.; Kawakami, Joel; Konkel, Michael J.; Boteju, Lakmal W.; Wetzel, John M.; Noble, Stewart A.; Wan, Honghe
Patent: US2003/176314 A1, 2003 ;
US 20030176314 A1
反应条件
iodine T=90°C; 16 h;
参考文献
Pooley, Charlotte L. F.; Edwards, James P.; Goldman, Mark E.; Wang, Ming-Wei; Marschke, Keith B.; Crombie, Diane L.; Jones, Todd K.
Journal of Medicinal Chemistry, 1998 , vol. 41, # 18 p. 3461 - 3466
反应条件
palladium diacetate; potassium fluoride; 2-dicyclohexylphosphino-1,1'-biphenyl in tetrahydrofuran; toluene T=20°C; Suzuki coupling; 16 h;
参考文献
Takahashi, Hidenori; Bekkali, Younes; Capolino, Alison J.; Gilmore, Thomas; Goldrick, Susan E.; Nelson, Richard M.; Terenzio, Donna; Wang, Ji; Zuvela-Jelaska, Ljiljana; Proudfoot, John; Nabozny, Gerald; Thomson, David
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 6 p. 1549 - 1552
