反应条件
1: 61 percent / phenyliodine(III) bis(trifluoroacetate) / 2,2,2-trifluoro-ethanol / 0.17 h / -40 °C 2: 95 percent / BCl3 / CH2Cl2 / 20 h / -78 °C 3: 83 percent / pyridine / 3 h / 0 °C 4: 98 percent / formic acid; Et3N; PPh3 / Pd(OAc)2 / dimethylformamide / 72 h / 60 °C 5: 78 percent / lithium tri-sec-butylborohydride / tetrahydrofuran / 3 h / -78 °C 6: 96 percent / TBAB; KOH / methanol / 24 h / 80 °C 7: NaBH4 / methanol / 24 h / 20 °C 8: 46.3 mg / 48 h / Heating 9: 94 percent / lithium aluminum hydride / tetrahydrofuran / 7 h / 20 °C View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 54, # 12 p. 1662 - 1679
