1-(4-甲氧基苯基)-1H-吡唑合成路线 (共 12 条)
反应条件
copper(I) oxide in methanol T=20°C; 12 h;
参考文献
Sreedhar, Bojja; Venkanna, Gopaladasu T.; Shiva Kumar, Kota Balaji; Balasubrahmanyam, Vura
Synthesis, 2008 , # 5 p. 795 - 799
反应条件
caesium carbonate; copper(II) oxide; iron (III) acetylacetonate in N,N-dimethyl-formamide T=90°C; 30 h;
参考文献
Arsenyan, Pavel; Paegle, Edgars; Petrenko, Alla; Belyakov, Sergey
Tetrahedron Letters, 2010 , vol. 51, # 38 p. 5052 - 5055
反应条件
o-hydroxybenzaldehyde oxime; caesium carbonate; copper(I) oxide in acetonitrile T=82°C; 40 h;
参考文献
Cristau, Henri-Jean; Cellier, Pascal P.; Spindler, Jean-Francis; Taillefer, Marc
European Journal of Organic Chemistry, 2004 , # 4 p. 695 - 709
反应条件
Cu(II)(MeCOCHCO2Et)2 in water T=40°C; P=760.051 Torr; 96 h;
参考文献
Joubert, Nicolas; Basle, Emmanuel; Vaultier, Michel; Pucheault, Mathieu
Tetrahedron Letters, 2010 , vol. 51, # 22 p. 2994 - 2997
反应条件
oxalic acid dihydrazide; phosphoric acid trihydrate; tetrabutylammomium bromide; hexane-2,5-dione; copper(II) oxide in water T=120°C; 48 h;
参考文献
Huang, Manna; Lin, Xiaoqin; Zhu, Xinhai; Peng, Weili; Xie, Jianwei; Wan, Yiqian
European Journal of Organic Chemistry, 2011 , # 24 p. 4523 - 4527
反应条件
[Ni0(1,5-cyclooctadiene)2]; 1,1,3,3-tetramethyldisiloxane; tri-cyclo-hexyl-phosphine in toluene T=110°C; 14 h; Inert atmosphere;
参考文献
Alvarez-Bercedo, Paula; Martin, Ruben
Journal of the American Chemical Society, 2010 , vol. 132, # 49 p. 17352 - 17353
反应条件
in ethanol 1 h; Reflux;
参考文献
Velcicky, Juraj; Feifel, Roland; Hawtin, Stuart; Heng, Richard; Huppertz, Christine; Koch, Guido; Kroemer, Markus; Moebitz, Henrik; Revesz, Laszlo; Scheufler, Clemens; Schlapbach, Achim
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 3 p. 1293 - 1297
反应条件
potassium hydroxide in dimethyl sulfoxide T=120°C; 48 h; Inert atmosphere;
参考文献
Journal of Organic Chemistry, , vol. 76, # 2 p. 654 - 660
反应条件
boron tribromide in dichloromethane T=-78 - 20°C; 19 h;
参考文献
deCODE genetics ehf.
Patent: US2008/33013 A1, 2008 ;
Location in patent: Page/Page column 7 ;
US 20080033013 A1
反应条件
1.1: trichlorophosphate / N,N-dimethyl-formamide / 0 - 110 °C 1.2: 0.5 h 2.1: NH2OH*H2O / formic acid / 6 h / Reflux View Scheme
参考文献
Dos Santos, Mauricio S.; Gomes, Adriana O.; Bernardino, Alice M. R.; De Souza, Marcos C.; Khan, Misbahul A.; De Brito, Monique A.; Castro, Helena C.; Abreu, Paula A.; Rodrigues, Carlos R.; De Leo, Rosa M. M.; Leon, Leonor L.; Canto-Cavalheirr, Marilene M.
Journal of the Brazilian Chemical Society, 2011 , vol. 22, # 2 p. 352 - 358