N-Cbz-L-谷氨酸-5-乙酯合成路线 （共 12 条）
反应条件
methanol; recombinant Bacillus subtilis esterase double mutant E188W/M193C in hexane T=37°C; pH=7.4; 0.416667 h; aq. phosphate bufferEnzymatic reaction; regioselective reaction;
参考文献
Barbayianni, Efrosini; Kokotos, Christoforos G.; Bartsch, Sebastian; Drakou, Christina; Bornscheuer, Uwe T.; Kokotos, George
Advanced Synthesis and Catalysis, 2009 , vol. 351, # 14-15 p. 2325 - 2332
反应条件
methanol; recombinant Bacillus subtilis esterase double mutant E188W/M193C in hexane T=37°C; pH=7.4; 0.333333 h; aq. phosphate bufferEnzymatic reaction; regioselective reaction;
参考文献
Barbayianni, Efrosini; Kokotos, Christoforos G.; Bartsch, Sebastian; Drakou, Christina; Bornscheuer, Uwe T.; Kokotos, George
Advanced Synthesis and Catalysis, 2009 , vol. 351, # 14-15 p. 2325 - 2332
反应条件
sodium hydroxide; sodium hydrogencarbonate
参考文献
Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, , vol. 219, p. 155
反应条件
methanol; Bacillus subtilis esterase in hexane T=37°C; pH=7.4; 0.5 h; aq. phosphate bufferEnzymatic reaction; regioselective reaction;
参考文献
Advanced Synthesis and Catalysis, , vol. 351, # 14-15 p. 2325 - 2332
反应条件
methanol; recombinant Bacillus subtilis esterase double mutant E188W/M193C in hexane T=37°C; pH=7.4; 0.75 h; aq. phosphate bufferEnzymatic reaction; regioselective reaction;
参考文献
Advanced Synthesis and Catalysis, , vol. 351, # 14-15 p. 2325 - 2332
反应条件
methanol; recombinant Bacillus subtilis esterase double mutant E188W/M193C in hexane T=37°C; pH=7.4; 0.416667 h; aq. phosphate bufferEnzymatic reaction;
参考文献
Advanced Synthesis and Catalysis, , vol. 351, # 14-15 p. 2325 - 2332
反应条件
1: HCl / Isolierung des Esters aus dem Hydrochlorid durch Umsetzung mit aethanol.Pyridin 2: MgO / unter Kuehlung View Scheme
参考文献
Helvetica Chimica Acta, , vol. 31, p. 737,743
反应条件
1: (i) Et3N, (ii) DCC, THF 2: aq. NaOH / methanol 3: H2 / Pd-C / methanol; H2O View Scheme
参考文献
Shiba,T.; Kaneko,T.
Bulletin of the Chemical Society of Japan, 1960 , vol. 33, p. 1721 - 1730
反应条件
1: hydrazine hydrate / 100 °C 2: NaNO2 / ueber mehrere Stufen 3: liquid ammonia; sodium View Scheme
参考文献
Hegedues
Helvetica Chimica Acta, 1948 , vol. 31, p. 737,743
反应条件
1: PCl5; diethyl ether / Behandeln einer Loesung des Reaktionsprodukts in Aether mit Glycin-benzylester 2: palladium; aqueous ethanol / Hydrogenation 3: chlorocarbonic acid benzyl ester; MgO; aqueous NaHCO3 4: concentrated aqueous NH3 View Scheme
参考文献
Miller; Waelsch
Archives of Biochemistry, 1952 , vol. 35, p. 176,179
