5'-N-甲基甲酰氨基腺苷合成路线 （共 6 条）
反应条件
trifluoroacetic acid 0.5 h; Ambient temperature;
参考文献
De Zwart, Maarten; Kourounakis, Angeliki; Kooijman, Huub; Spek, Anthony L.; Link, Regina; Von Frijtag Drabbe Kuenzel, Jacobien K.; IJzerman, Ad P.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 8 p. 1384 - 1392
反应条件
in tetrahydrofuran T=110°C; 0.333333 h; microwave irradiation;
参考文献
Devine, Shane M.; Scammells, Peter J.
Tetrahedron, 2008 , vol. 64, # 8 p. 1772 - 1777
反应条件
1: 1-[3-(dimethylamino)propyl]-3-ethylcarbodiimide*HCl / dimethylformamide / 3 h / 20 °C 2: dimethylformamide / 1 h / 20 °C 3: 80percent aq. TFA / 20 °C View Scheme
参考文献
De Zwart, Maarten; Kourounakis, Angeliki; Kooijman, Huub; Spek, Anthony L.; Link, Regina; Von Frijtag Drabbe Kuenzel, Jacobien K.; IJzerman, Ad P.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 8 p. 1384 - 1392
反应条件
1: dimethylformamide / 1 h / 20 °C 2: 80percent aq. TFA / 20 °C View Scheme
参考文献
Umino; Yoshioka; Saitoh; Minakawa; Nakata; Matsuda
Journal of Medicinal Chemistry, 2001 , vol. 44, # 2 p. 208 - 214
参考文献
Prasad, Raj Nandan; Bariana, Dilbagh S.; Fung, Anthony; Savic, Milica; Tietje, Karin; et al.
Journal of Medicinal Chemistry, 1980 , vol. 23, # 3 p. 313 - 319
反应条件
1: 77 percent / ethanol / 6 h / Heating 2: 72 percent / NaBH4 / tetrahydrofuran / 8 h / Heating View Scheme
参考文献
Afify, Hanan M. N. M.; Pedersen, Erik B.; Zahran, Magdy A.
Journal of Heterocyclic Chemistry, 2000 , vol. 37, # 2 p. 339 - 341
