(2RS)-2-(4-乙基苯基)丙酸合成路线 （共 7 条）
反应条件
triethylamine in n-butyllithium; water
参考文献
Mine Safety Appliances Company
Patent: US4910337 A1, 1990 ;
反应条件
water; methyloxirane in acetone 3 h; Irradiation;
参考文献
Sonawane, Harikisan R.; Kulkarni, Dilip G.; Ayyangar, Nagaraj R.
Tetrahedron Letters, 1990 , vol. 31, # 51 p. 7495 - 7496
反应条件
methyloxirane in water; acetone IrradiationpH neutral;
参考文献
Sonawane, Harikisan; Bellur, Nanjundiah S.; Kulkarni, Dilip G.; Ayyangar, Nagaraj R.
Tetrahedron, 1994 , vol. 50, # 4 p. 1243 - 1260
反应条件
1: AlCl3 2: 82 percent / propylene oxide / H2O; acetone / Irradiation; pH neutral View Scheme
参考文献
Sonawane, Harikisan; Bellur, Nanjundiah S.; Kulkarni, Dilip G.; Ayyangar, Nagaraj R.
Tetrahedron, 1994 , vol. 50, # 4 p. 1243 - 1260
反应条件
sodium hydroxide in ethanol; water 6 h; Ambient temperature; Yield given;
参考文献
Amano; Yoshikawa; Ogawa; Sano; Ohuchi; Tanami; Ota; Hatayama; Higuchi; Amanuma
Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 11 p. 4653 - 4662
反应条件
1: 1.) magnesium, 1,2-dibromoethane, iodine; 2.) NiCl2 / 1.) THF, 60-65 deg C, 30 min; 2.) reflux, 4 h; 3.) THF, r.t., 4.5 h 2: NaOH / ethanol; H2O / 6 h / Ambient temperature View Scheme
参考文献
Amano; Yoshikawa; Ogawa; Sano; Ohuchi; Tanami; Ota; Hatayama; Higuchi; Amanuma
Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 11 p. 4653 - 4662
反应条件
n-butyllithium; potassium tert-butylate 1) hexane; Yield given. Multistep reaction;
参考文献
Faigl; Schlosser
Tetrahedron Letters, 1991 , vol. 32, # 28 p. 3369 - 3370
