双[2,8-二(三氟甲基)喹啉-4-基-2-吡啶基]酮合成路线 （共 12 条）
反应条件
in diethyl ether T=-78°C; 0.166667 h;
参考文献
US6664397 B1, ;
Page column 7-8 ;
反应条件
dihydrogen peroxide; acetic acid T=70°C; 1 h;
参考文献
Adam, Solange
Tetrahedron, 1991 , vol. 47, # 36 p. 7609 - 7614
反应条件
sodium hydroxide in diethyl ether 0.166667 h; Ambient temperature;
参考文献
Adam, Solange
Tetrahedron, 1991 , vol. 47, # 36 p. 7609 - 7614
反应条件
tetrabutyl ammonium fluoride in acetonitrile 0.166667 h; Ambient temperature;
参考文献
Tetrahedron, , vol. 45, # 5 p. 1409 - 1414
反应条件
1: 90 percent / NaH / toluene; dimethylformamide / 20 h / 110 °C 2: 0.5 g / BuLi / tetrahydrofuran; hexane / Ambient temperature 3: 40 percent / TBAF / acetonitrile / 0.17 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 45, # 5 p. 1409 - 1414
反应条件
1: 90 percent / NaH / toluene; dimethylformamide / 20 h / 110 °C 2: 0.5 g / BuLi / tetrahydrofuran; hexane / Ambient temperature 3: 40 percent / TBAF / acetonitrile / 0.17 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 45, # 5 p. 1409 - 1414
反应条件
1: 0.5 g / BuLi / tetrahydrofuran; hexane / Ambient temperature 2: 40 percent / TBAF / acetonitrile / 0.17 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 45, # 5 p. 1409 - 1414
反应条件
1: 1.) NaH / 1.) toluene, DMF, 0 - 5 deg C, 1 h, 2.) toluene, DMF, 5 - 10 deg C, 2 h 2: 95 percent / 30percent H2O2, acetic acid / 1 h / 70 °C View Scheme
参考文献
Tetrahedron, , vol. 47, # 36 p. 7609 - 7614
反应条件
1: 1.) NaH / 1.) toluene, DMF, 0 - 5 deg C, 1 h, 2.) toluene, DMF, 5 - 10 deg C, 2 h 2: 95 percent / 30percent H2O2, acetic acid / 1 h / 70 °C View Scheme
参考文献
Tetrahedron, , vol. 47, # 36 p. 7609 - 7614
反应条件
tetrabutyl ammonium fluoride; oxygen in acetonitrile Ambient temperature; Yield given;
参考文献
Tetrahedron, , vol. 45, # 5 p. 1409 - 1414
