3-苯基咪唑并[1,5-a]吡啶合成路线 （共 15 条）
反应条件
2-methoxy-pyridine; trifluoromethylsulfonic anhydride in dichloromethane T=35°C; 16 h; Inert atmosphere; ConcentrationReagent/catalystTemperatureTime;
参考文献
Pelletier, Guillaume; Charette, Andre B.
Organic Letters, 2013 , vol. 15, # 9 p. 2290 - 2293
反应条件
pyridine; iodine in tetrahydrofuran T=0 - 20°C;
参考文献
Shibahara, Fumitoshi; Kitagawa, Asumi; Yamaguchi, Eiji; Murai, Toshiaki
Organic Letters, 2006 , vol. 8, # 24 p. 5621 - 5624
反应条件
trichlorophosphate T=150°C; 0.75 h; Microwave irradiation;
参考文献
Arvapalli, Venkata Satyanarayana; Chen, Guangwu; Kosarev, Sergey; Tan, Meifen Evonne; Xie, Dejian; Yet, Larry
Tetrahedron Letters, 2010 , vol. 51, # 2 p. 284 - 286
反应条件
1-propanephosphonic acid cyclic anhydride in acetic acid n-butyl ester; ethyl acetate T=20°C; 18 h; Reflux;
参考文献
Crawforth, James M.; Paoletti, Melissa
Tetrahedron Letters, 2009 , vol. 50, # 34 p. 4916 - 4918
反应条件
tetra-n-butylammonium acetate; palladium diacetate; triphenylphosphine in toluene T=100°C; Inert atmosphere; regioselective reaction;
参考文献
Huang, Chunhui; Giokaris, Alexandros; Gevorgyan, Vladimir
Chemistry Letters, 2011 , vol. 40, # 9 p. 1053 - 1054
反应条件
[Pd(phen)2(PF6)2]; caesium carbonate in dimethylammonium 2,4-dichlorophenoxyacetate T=150°C; 20 h; Inert atmosphere; regioselective reaction;
参考文献
Yamaguchi, Eiji; Shibahara, Fumitoshi; Murai, Toshiaki
Chemistry Letters, 2011 , vol. 40, # 9 p. 939 - 940
反应条件
iodine; potassium hydrogencarbonate in N,N-dimethyl acetamide T=20°C; 4 h; Molecular sieve;
参考文献
Wang, Qiang; Zhang, Shuai; Guo, Fengfeng; Zhang, Baiqun; Hu, Ping; Wang, Zhiyong
Journal of Organic Chemistry, 2012 , vol. 77, # 24 p. 11161 - 11166
反应条件
1: alumina / 2.5 h 2: sulfur; 2-(aminomethyl)pyridine / dimethylformamide / 3 h / 80 - 90 °C 3: 84 percent / iodine; pyridine / tetrahydrofuran / 0 - 20 °C View Scheme
参考文献
Kamal, Ahmed; Ramakrishna; Raju; Rao, A.V. Subba; Viswanath; Nayak, V. Lakshma; Ramakrishna, Sistla
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 6 p. 2427 - 2435
反应条件
1: alumina / 2.5 h 2: sulfur; 2-(aminomethyl)pyridine / dimethylformamide / 3 h / 80 - 90 °C 3: 84 percent / iodine; pyridine / tetrahydrofuran / 0 - 20 °C View Scheme
参考文献
Shibahara, Fumitoshi; Kitagawa, Asumi; Yamaguchi, Eiji; Murai, Toshiaki
Organic Letters, 2006 , vol. 8, # 24 p. 5621 - 5624
反应条件
1: sulfur; 2-(aminomethyl)pyridine / dimethylformamide / 3 h / 80 - 90 °C 2: 84 percent / iodine; pyridine / tetrahydrofuran / 0 - 20 °C View Scheme
参考文献
Shibahara, Fumitoshi; Kitagawa, Asumi; Yamaguchi, Eiji; Murai, Toshiaki
Organic Letters, 2006 , vol. 8, # 24 p. 5621 - 5624
