顺式-四氢-1H-环戊并[c]呋喃-1,3(3aH)-二酮合成路线 （共 14 条）
反应条件
acetic anhydride 20 h; Reflux;
参考文献
MEDIVIR AB; AYESA, Susana; BELDA, Oscar; BJÖRKLUND, Catarina; NILSSON, Magnus; RUSSO, Francesco; SAHLBERG, Christer; WIKTELIUS, Daniel
Patent: WO2013/95275 A1, 2013 ;
Location in patent: Page/Page column 35 ;
反应条件
1: Br2 / CH2Cl2 2: aq. KOH; aq. HCl 3: AcOAc View Scheme
参考文献
Journal of the American Chemical Society, , vol. 122, # 50 p. 12610 - 12611
反应条件
1: aq. KOH; aq. HCl 2: AcOAc View Scheme
参考文献
Journal of the American Chemical Society, , vol. 122, # 50 p. 12610 - 12611
参考文献
Tetrahedron Letters, , vol. 30, # 1 p. 67 - 68
反应条件
1: aq. KOH / tetrahydrofuran 2: (EtCO)2O / 135 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 3 p. 433 - 436
反应条件
1: aq. potassium hydroxide / 2 h / 0 °C 2: 85 percent / acetic anhydride / 10 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 54, # 4 p. 817 - 824
反应条件
trifluoroacetic anhydride
参考文献
Angewandte Chemie, , vol. 96, # 1 p. 55 - 56
反应条件
1: 24 h / 60 °C / |Inert atmosphere 2: lithium diisopropyl amide / 4 h / -78 °C / |Inert atmosphere View Scheme
参考文献
MEDIVIR AB; AYESA, Susana; BELDA, Oscar; BJÖRKLUND, Catarina; NILSSON, Magnus; RUSSO, Francesco; SAHLBERG, Christer; WIKTELIUS, Daniel
Patent: WO2013/95275 A1, 2013 ;
反应条件
1: 24 h / 60 °C / |Inert atmosphere 2: lithium diisopropyl amide / 4 h / -78 °C / |Inert atmosphere View Scheme
参考文献
MEDIVIR AB; AYESA, Susana; BELDA, Oscar; BJÖRKLUND, Catarina; NILSSON, Magnus; RUSSO, Francesco; SAHLBERG, Christer; WIKTELIUS, Daniel
Patent: WO2013/95275 A1, 2013 ;
