2,3,4,5-四甲氧基甲苯合成路线 （共 45 条）
反应条件
sodium hydroxide in ethanol T=20 - 80°C;
参考文献
Vera, William J.; Chinea, Kimberly; Banerjee, Ajoy K.
Journal of Chemical Research, 2009 , # 3 p. 186 - 187
反应条件
copper(l) chloride in methanol; N,N-dimethyl-formamide T=110°C; 8 h; Inert atmosphere;
参考文献
Wang, Jin; Yang, Jian; Yang, Bo; Hu, Xiao; Sun, Jia-Qiang; Yang, Tao
Journal of Chemical Research, 2010 , vol. 34, # 12 p. 717 - 718
反应条件
hydrogenchloride; palladium on activated charcoal; hydrogen in acetic acid 120 h;
参考文献
Syper, L.; Kloc, K.; Mlochowski, J.
Tetrahedron, 1980 , vol. 36, # 1 p. 123 - 129
反应条件
ethanol; magnesium T=40 - 45°C; 2 h;
参考文献
Yang, Jian; Weng, Lingling; Zheng, Hu
Synthetic Communications, 2006 , vol. 36, # 16 p. 2401 - 2405
反应条件
n-butyllithium; N,N,N',N,-tetramethylethylenediamine 1.) THF, hexane, 0 deg C, 2.) THF, hexane, 0 deg C; Yield givenMultistep reaction;
参考文献
Journal of the American Chemical Society, , vol. 121, # 15 p. 3799 - 3800
反应条件
1: 88 percent / Fe; Br2 / CHCl3 / 4 h / 20 °C 2: 66 percent / CuCN; Me2CO3 / 1,2-dimethoxy-ethane; methanol / 120 h / 80 °C 3: K2CO3 / acetone / 6 h / Heating View Scheme
参考文献
Organic Letters, , vol. 7, # 12 p. 2417 - 2420
反应条件
1: 66 percent / CuCN; Me2CO3 / 1,2-dimethoxy-ethane; methanol / 120 h / 80 °C 2: K2CO3 / acetone / 6 h / Heating View Scheme
参考文献
Organic Letters, , vol. 7, # 12 p. 2417 - 2420
反应条件
potassium carbonate in acetone 6 h; Heating;
参考文献
Organic Letters, , vol. 7, # 12 p. 2417 - 2420
反应条件
1: 90 percent / HCl / hexane / 20 °C 2: 94 percent / magnesium; ethanol / 2 h / 40 - 45 °C View Scheme
参考文献
Synthetic Communications, , vol. 36, # 16 p. 2401 - 2405
反应条件
1: 66 percent / 0.5M aq. H2SO4 / 9 h 2: 69 percent / NaOH 3: 1.) n-BuLi, TMEDA / 1.) THF, hexane, 0 deg C, 2.) THF, hexane, 0 deg C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 121, # 15 p. 3799 - 3800
