sulfuric acid T=40°C; overnight;

sodium hydroxide T=100°C; 2 h;

1: liquid ammonia / 5 h / Heating 2: 75.5 percent / 0.1 M sulfuric acid / 40 °C / overnight View Scheme

1: 80 percent / hydrogen chloride / acetone; dimethylformamide / Ambient temperature 2: liquid ammonia / 5 h / Heating 3: 75.5 percent / 0.1 M sulfuric acid / 40 °C / overnight View Scheme

1: 88 percent / thionyl chloride / hexamethylphosphoric acid triamide / 2 h / 0 °C / r.t., overnight 2: 80 percent / hydrogen chloride / acetone; dimethylformamide / Ambient temperature 3: liquid ammonia / 5 h / Heating 4: 75.5 percent / 0.1 M sulfuric acid / 40 °C / overnight View Scheme

human placental AdoHcy hydrolase T=37°C; 0.0833333 h;