N-(苄氧羰基)-L-苯丙氨酸甲酯合成路线 (共 61 条)
反应条件
in 1,4-dioxane 7 h; Heating; Yield given. Yields of byproduct given;
参考文献
Matsumura, Noboru; Noguchi, Akiko; Kitayoshi, Aya; Inoue, Hiroo
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1995 , # 23 p. 2953 - 2954
反应条件
anhydrous potassium trimethylsilanolate in diethyl ether T=20°C; 16 h;
参考文献
Synthesis, , # 4 art. no. P12804SS, p. 569 - 574
反应条件
ruthenium trichloride; sodium periodate in tetrachloromethane; acetonitrile 60 h;
参考文献
Ranganathan; Muraleedharan; Bhattacharyya; Kundu
Journal of the Indian Chemical Society, 1998 , vol. 75, # 10-12 p. 583 - 589
反应条件
stannous bromide; triethylamine in dichloromethane T=20°C; Substitution; 9 h; Product distribution; Further Variations:ReagentsSolvents;
参考文献
Li, Wen-Ren; Yo, Ying-Chih; Lin, Yu-Sheng
Tetrahedron, 2000 , vol. 56, # 45 p. 8867 - 8875
反应条件
1: 90 percent / p-TsOH / toluene / 100 °C 2: NaHCO3 / methanol; H2O / Heating 3: H2 / Pd/C / methanol / 12 h / 20 °C 4: HCl / 12 h / 20 °C View Scheme
参考文献
Allevi, Pietro; Anastasia, Mario
Tetrahedron Letters, 2003 , vol. 44, # 41 p. 7663 - 7665
反应条件
hydrogenchloride; hydrogen; acetic acid in water
参考文献
Synthesis, , # 20 art. no. N44611SS, p. 3247 - 3254
反应条件
sodium tetrahydroborate; acetic acid in 1,4-dioxane T=80°C;
参考文献
Soucek, Milan; Urban, Jan; Saman, David
Collection of Czechoslovak Chemical Communications, 1990 , vol. 55, # 3 p. 761 - 765
反应条件
in tetrahydrofuran; water; acetic acid; ethyl acetate
参考文献
Abbott Laboratories
Patent: US5362912 A1, 1994 ;
反应条件
TiCl2(OPri)2; diisobutylaluminium hydride 1.) CH2Cl2, toluene, -78 deg C, 2 h, 2.) CH2Cl2, -78 deg C, 3 h; Yield given. Multistep reaction;
参考文献
Kiyooka; Suzuki; Shirouchi; Kaneko; Tanimori
Tetrahedron Letters, 1993 , vol. 34, # 36 p. 5729 - 5732
反应条件
TiCl2(OPri)2; diisobutylaluminium hydride 1.) CH2Cl2, toluene, -78 deg C; Yield given. Multistep reaction;
参考文献
Kiyooka; Suzuki; Shirouchi; Kaneko; Tanimori
Tetrahedron Letters, 1993 , vol. 34, # 36 p. 5729 - 5732