4- 雌-3Alpha,17Β-二醇合成路线 （共 6 条）
参考文献
Nambara,T. et al.
Chemical and Pharmaceutical Bulletin, 1972 , vol. 20, # 2 p. 287 - 294
反应条件
1: LiAlH4; diethyl ether / Behandeln des Reaktionsprodukts mit Acetanhydrid und Pyridin 2: aqueous methanol. KOH View Scheme
参考文献
Hartman
Journal of the American Chemical Society, 1955 , vol. 77, p. 5151,5153
反应条件
potassium tri-sec-butyl-borohydride in tetrahydrofuran 1.) -78 deg C, 15 h, 2) -10 deg C, 3 h; Title compound not separated from byproducts;
参考文献
Han, Mingcheng; Zorumski, Charles F.; Covey, Douglas F.
Journal of Medicinal Chemistry, 1996 , vol. 39, # 21 p. 4218 - 4232
反应条件
1: SOCl2, Py 2: KOH / methanol View Scheme
参考文献
Nambara,T. et al.
Chemical and Pharmaceutical Bulletin, 1972 , vol. 20, # 2 p. 287 - 294
反应条件
lithium aluminium tetrahydride; diethyl ether
参考文献
Searle and Co.
Patent: DE1010964 , 1957 ;
Full Text Show Details
Searle and Co.
Patent: US2843608 , 1956 ;
反应条件
lithium aluminium tetrahydride; diethyl ether
参考文献
Searle and Co.
Patent: DE1010964 , 1957 ;
Full Text Show Details
Searle and Co.
Patent: US2843608 , 1956 ;
