4-羟基-8-甲基喹啉-3-甲酸合成路线 （共 4 条）
反应条件
1: various solvent(s) / 1 h / Heating 2: aq. NaOH / 1 h / Heating View Scheme
参考文献
Golub, Andriy G.; Yakovenko, Olexander Ya.; Bdzhola, Volodymyr G.; Sapelkin, Vladislav M.; Zien, Piotr; Yarmoluk, Sergiy M.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 22 p. 6443 - 6450
反应条件
1: 1 h / Heating 2: various solvent(s) / 1 h / Heating 3: aq. NaOH / 1 h / Heating View Scheme
参考文献
Brogi, Simone; Corelli, Federico; Di Marzo, Vincenzo; Ligresti, Alessia; Mugnaini, Claudia; Pasquini, Serena; Tafi, Andrea
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 2 p. 547 - 555
反应条件
sodium hydroxide 1 h; Heating;
参考文献
Golub, Andriy G.; Yakovenko, Olexander Ya.; Bdzhola, Volodymyr G.; Sapelkin, Vladislav M.; Zien, Piotr; Yarmoluk, Sergiy M.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 22 p. 6443 - 6450
反应条件
paraffin oil T=280°C;
参考文献
Roberts
Journal of Organic Chemistry, 1949 , vol. 14, p. 277,280
