1: ethyl acetoacetate With potassium tert-butylate in isopropyl alcohol T=30 - 40°C; Inert atmosphere; 2: 2-Chloropyridine-3-carboxylic acid With copper diacetate in isopropyl alcohol T=35 - 78°C; 4 h; Inert atmosphere; 3: With hydrogenchloride in water; isopropyl alcohol T=30°C; pH=6 - 7;

1: ethyl acetoacetate; isopropyl alcohol With potassium tert-butylate T=30 - 40°C; Inert atmosphere; 2: 2-Chloropyridine-3-carboxylic acid With copper diacetate T=78°C; 4 h; Inert atmosphere;