4-氯-6-苯基噻吩并[2,3-D]嘧啶合成路线 （共 10 条）
反应条件
N,N-dimethyl-formamide; trichlorophosphate in 1,2-dichloro-ethane T=65°C; 1 h;
参考文献
Organic Letters, , vol. 6, # 12 p. 1991 - 1994
反应条件
tris-(dibenzylideneacetone)dipalladium(0); potassium carbonate in 1,4-dioxane T=130°C; Suzuki Coupling; 5 h; ConcentrationSolventTemperatureTime;
参考文献
Tetrahedron, , vol. 68, # 45 p. 9226 - 9233
反应条件
1: 100 percent / 2.5 h / 190 °C 2: 85 percent / POCl3; DMF / 1,2-dichloro-ethane / 1 h / 65 °C View Scheme
参考文献
Organic Letters, , vol. 6, # 12 p. 1991 - 1994
反应条件
1: 64 percent / sulphur; Et3N / ethanol / 20 - 60 °C 2: 100 percent / 2.5 h / 190 °C 3: 85 percent / POCl3; DMF / 1,2-dichloro-ethane / 1 h / 65 °C View Scheme
参考文献
Organic Letters, , vol. 6, # 12 p. 1991 - 1994
反应条件
tetrakis(triphenylphosphine) palladium(0); potassium carbonate in 1,4-dioxane; water T=110°C; Suzuki Coupling; 6 h; ConcentrationSolventTemperatureTime;
参考文献
Tetrahedron, , vol. 68, # 45 p. 9226 - 9233
反应条件
1: acetic acid; bromine / 3 h / 80 °C 2: trichlorophosphate / 3 h / 120 °C 3: tris-(dibenzylideneacetone)dipalladium(0); potassium carbonate / 1,4-dioxane / 5 h / 130 °C View Scheme
参考文献
Tetrahedron, , vol. 68, # 45 p. 9226 - 9233
反应条件
1: trichlorophosphate / 3 h / 120 °C 2: tris-(dibenzylideneacetone)dipalladium(0); potassium carbonate / 1,4-dioxane / 5 h / 130 °C View Scheme
参考文献
Tetrahedron, , vol. 68, # 45 p. 9226 - 9233
反应条件
1: acetic acid; bromine / 3 h / 80 °C 2: trichlorophosphate / 3 h / 120 °C 3: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / 1,4-dioxane / 24 h / 110 °C View Scheme
参考文献
Tetrahedron, , vol. 68, # 45 p. 9226 - 9233
反应条件
1: trichlorophosphate / 3 h / 120 °C 2: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / 1,4-dioxane / 24 h / 110 °C View Scheme
参考文献
Tetrahedron, , vol. 68, # 45 p. 9226 - 9233
反应条件
hydrazine hydrate in ethanol
参考文献
Arya,V.P.; Ghate,S.P.
Indian Journal of Chemistry, 1971 , vol. 9, p. 1209 - 1212
