5,8-二氯-4-羟基喹啉-3-羧酸乙酯合成路线 （共 5 条）
反应条件
1: T=100°C; Gould-Jacobs reaction; 3 h; 2: in diphenylether T=250°C; Gould-Jacobs reaction; 2 h; Inert atmosphere;
参考文献
Li, Guo-Xiang; Liu, Zai-Qun; Luo, Xu-Yang
European Journal of Medicinal Chemistry, 2010 , vol. 45, # 5 p. 1821 - 1827
反应条件
dowtherm A T=250°C; 1 h; Yield given;
参考文献
Podanyi, Benjamin; Kereszturi, Geza; Vasvari-Debreczy, Lelle; Chinoin, Istvan Hermecz; Toth, Gabor
Magnetic Resonance in Chemistry, 1996 , vol. 34, # 11 p. 972 - 978
反应条件
1: 115 - 120 °C / 30-60 min 2: Dowtherm A / 1 h / 250 °C View Scheme
参考文献
Podanyi, Benjamin; Kereszturi, Geza; Vasvari-Debreczy, Lelle; Chinoin, Istvan Hermecz; Toth, Gabor
Magnetic Resonance in Chemistry, 1996 , vol. 34, # 11 p. 972 - 978
反应条件
1: 115 - 120 °C / 30-60 min 2: Dowtherm A / 1 h / 250 °C View Scheme
参考文献
Podanyi, Benjamin; Kereszturi, Geza; Vasvari-Debreczy, Lelle; Chinoin, Istvan Hermecz; Toth, Gabor
Magnetic Resonance in Chemistry, 1996 , vol. 34, # 11 p. 972 - 978
反应条件
1: With water; potassium hydroxide Reflux; 2: With hydrogenchloride in water T=20°C; pH=2;
参考文献
Li, Guo-Xiang; Liu, Zai-Qun; Luo, Xu-Yang
European Journal of Medicinal Chemistry, 2010 , vol. 45, # 5 p. 1821 - 1827
