2-氨基-4-(4-氟苯基)噻吩-3-甲酸乙酯合成路线 （共 3 条）
反应条件
sulfur; 1,8-diazabicyclo[5.4.0]undec-7-ene in toluene T=120°C; Gewald reaction; 0.333333 h; microwave irradiation;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 7 p. 1885 - 1889
参考文献
Golub, Andriy G.; Bdzhola, Volodymyr G.; Briukhovetska, Nadiia V.; Balanda, Anatoliy O.; Kukharenko, Olexander P.; Kotey, Igor M.; Ostrynska, Olga V.; Yarmoluk, Sergiy M.
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 3 p. 870 - 876
反应条件
1: 24 h / 160 - 170 °C
2: phosphorus pentachloride; trichlorophosphate
View Scheme
参考文献
Golub, Andriy G.; Bdzhola, Volodymyr G.; Briukhovetska, Nadiia V.; Balanda, Anatoliy O.; Kukharenko, Olexander P.; Kotey, Igor M.; Ostrynska, Olga V.; Yarmoluk, Sergiy M.
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 3 p. 870 - 876
