5-(4-氟苯基)-3H-噻吩并[2,3-d]嘧啶-4-酮合成路线 （共 5 条）
反应条件
acetic anhydride T=110°C; 36 h; Inert atmosphere;
参考文献
Zhao, Ailing; Gao, Xin; Wang, Yuanxiang; Ai, Jing; Wang, Ying; Chen, Yi; Geng, Meiyu; Zhang, Ao
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 13 p. 3906 - 3918
参考文献
Indian Journal of Chemistry, , vol. 9, p. 1209 - 1212
反应条件
1: sulfur; triethylamine / diethyl ether / 12 h / 20 °C 2: 24 h / 160 - 170 °C View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 46, # 3 p. 870 - 876
反应条件
1: sulfur; sodium hydrogencarbonate / tetrahydrofuran; water / 35 °C / Inert atmosphere 2: acetic anhydride / 36 h / 110 °C / Inert atmosphere View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 19, # 13 p. 3906 - 3918
反应条件
trichlorophosphate
T=100°C; 1 h; Inert atmosphere;
参考文献
Zhao, Ailing; Gao, Xin; Wang, Yuanxiang; Ai, Jing; Wang, Ying; Chen, Yi; Geng, Meiyu; Zhang, Ao
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 13 p. 3906 - 3918
