甲基3-(3,4-二羟基苯基)丙酸酯合成路线 （共 19 条）
反应条件
Agaricus bisporus; oxygen in aq. phosphate buffer; dichloromethane T=25°C; pH=7; 24 h; Reagent/catalyst;
参考文献
Bozzini, Tiziana; Botta, Giorgia; Delfino, Michela; Onofri, Silvano; Saladino, Raffaele; Amatore, Donatella; Sgarbanti, Rossella; Nencioni, Lucia; Palamara, Anna Teresa
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 24 p. 7699 - 7708
反应条件
thionyl chloride T=-40 - 20°C; 24 h;
参考文献
Northwestern University
Patent: US8227628 B2, 2012 ;
Location in patent: Page/Page column 30 ;
反应条件
hydrogen; palladium on activated charcoal in ethanol
参考文献
Percec, Virgil; Peterca, Mihai; Sienkowska, Monika J.; Ilies, Marc A.; Aqad, Emad; Smidrkal, Jan; Heiney, Paul A.
Journal of the American Chemical Society, 2006 , vol. 128, # 10 p. 3324 - 3334
反应条件
palladium 10 on activated carbon; hydrogen in methanol 24 h;
参考文献
Takahashi, Keisuke; Yoshioka, Yasuyuki; Kato, Eisuke; Katsuki, Shigeki; Iida, Osamu; Hosokawa, Keizo; Kawabata, Jun
Bioscience, Biotechnology and Biochemistry, 2010 , vol. 74, # 4 p. 741 - 745
反应条件
1: 90 percent / morpholine; AcOH / Heating 2: 95 percent / p-toluenesulfonic acid monohydrate / 24 h / Heating 3: 91 percent / H2 / Pd/C / ethanol View Scheme
参考文献
Percec, Virgil; Peterca, Mihai; Sienkowska, Monika J.; Ilies, Marc A.; Aqad, Emad; Smidrkal, Jan; Heiney, Paul A.
Journal of the American Chemical Society, 2006 , vol. 128, # 10 p. 3324 - 3334
反应条件
1: H2SO4 / Heating 2: 86 percent / K2CO3 / dimethylformamide / 8 h / 75 °C 3: 94 percent / LiAlH4 / tetrahydrofuran / 0 - 20 °C 4: pyridinium chlorochromate / CH2Cl2 / 20 °C 5: 90 percent / morpholine; AcOH / Heating 6: 95 percent / p-toluenesulfonic acid monohydrate / 24 h / Heating 7: 91 percent / H2 / Pd/C / ethanol View Scheme
参考文献
Percec, Virgil; Peterca, Mihai; Sienkowska, Monika J.; Ilies, Marc A.; Aqad, Emad; Smidrkal, Jan; Heiney, Paul A.
Journal of the American Chemical Society, 2006 , vol. 128, # 10 p. 3324 - 3334
反应条件
1: 86 percent / K2CO3 / dimethylformamide / 8 h / 75 °C 2: 94 percent / LiAlH4 / tetrahydrofuran / 0 - 20 °C 3: pyridinium chlorochromate / CH2Cl2 / 20 °C 4: 90 percent / morpholine; AcOH / Heating 5: 95 percent / p-toluenesulfonic acid monohydrate / 24 h / Heating 6: 91 percent / H2 / Pd/C / ethanol View Scheme
参考文献
Percec, Virgil; Peterca, Mihai; Sienkowska, Monika J.; Ilies, Marc A.; Aqad, Emad; Smidrkal, Jan; Heiney, Paul A.
Journal of the American Chemical Society, 2006 , vol. 128, # 10 p. 3324 - 3334
反应条件
1: pyridinium chlorochromate / CH2Cl2 / 20 °C 2: 90 percent / morpholine; AcOH / Heating 3: 95 percent / p-toluenesulfonic acid monohydrate / 24 h / Heating 4: 91 percent / H2 / Pd/C / ethanol View Scheme
参考文献
Percec, Virgil; Peterca, Mihai; Sienkowska, Monika J.; Ilies, Marc A.; Aqad, Emad; Smidrkal, Jan; Heiney, Paul A.
Journal of the American Chemical Society, 2006 , vol. 128, # 10 p. 3324 - 3334
反应条件
1: 95 percent / p-toluenesulfonic acid monohydrate / 24 h / Heating 2: 91 percent / H2 / Pd/C / ethanol View Scheme
参考文献
Percec, Virgil; Peterca, Mihai; Sienkowska, Monika J.; Ilies, Marc A.; Aqad, Emad; Smidrkal, Jan; Heiney, Paul A.
Journal of the American Chemical Society, 2006 , vol. 128, # 10 p. 3324 - 3334
反应条件
1: 94 percent / LiAlH4 / tetrahydrofuran / 0 - 20 °C 2: pyridinium chlorochromate / CH2Cl2 / 20 °C 3: 90 percent / morpholine; AcOH / Heating 4: 95 percent / p-toluenesulfonic acid monohydrate / 24 h / Heating 5: 91 percent / H2 / Pd/C / ethanol View Scheme
参考文献
Percec, Virgil; Peterca, Mihai; Sienkowska, Monika J.; Ilies, Marc A.; Aqad, Emad; Smidrkal, Jan; Heiney, Paul A.
Journal of the American Chemical Society, 2006 , vol. 128, # 10 p. 3324 - 3334
