N-生物素-3,6,9-三氧杂十一烷-1,11-二胺合成路线 （共 7 条）
反应条件
water; triphenylphosphine in tetrahydrofuran T=20°C; Staudinger reaction; 12 h;
参考文献
Fusz, Stefan; Srivatsan, Seergazhi G.; Ackermann, Damian; Famulok, Michael
Journal of Organic Chemistry, 2008 , vol. 73, # 13 p. 5069 - 5077
反应条件
reaget K25 T=20°C; 1.5 h;
参考文献
McReynolds, Katherine D.; Bhat, Abhijit; Conboy, John C.; Saavedra; Gervay-Hague, Jacquelyn
Bioorganic and Medicinal Chemistry, 2002 , vol. 10, # 3 p. 625 - 637
反应条件
1: 45 percent / DMAP / tetrahydrofuran / 3 h / 20 °C 2: 503 mg / TEA / dimethylformamide / 20 h 3: 52 percent / reaget K25 / 1.5 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 10, # 3 p. 625 - 637
反应条件
1: 503 mg / TEA / dimethylformamide / 20 h 2: 52 percent / reaget K25 / 1.5 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 10, # 3 p. 625 - 637
反应条件
1: 503 mg / TEA / dimethylformamide / 20 h 2: 52 percent / reaget K25 / 1.5 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 10, # 3 p. 625 - 637
反应条件
1: TEA / dimethylformamide / 4 h / 0 - 20 °C 2: 503 mg / TEA / dimethylformamide / 20 h 3: 52 percent / reaget K25 / 1.5 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 10, # 3 p. 625 - 637
反应条件
trifluoromethanesulfonyl azide; copper(II) sulfate; triethylamine in methanol; dichloromethane; water T=0 - 25°C;
参考文献
Yun, Wang; Shougang, Hu; Fast, Walter
Journal of the American Chemical Society, 2009 , vol. 131, # 42 p. 15096 - 15097
