5-氨基-4-咪唑甲酰胺合成路线 （共 23 条）
反应条件
in water; dimethyl sulfoxide T=37.5°C; decomposition half-life; pH=7.1;
参考文献
Canadian Journal of Chemistry, , vol. 59, # 9 p. 1347 - 1356
参考文献
Res.Rep.Nagoya ind.Sci.Res.Inst.Chem.Abstr., , # 9 p. 83
Res.Rep.Nagoya ind.Sci.Res.Inst.Chem.Abstr., , p. 12074
反应条件
1: With hydrogenchloride; sodium nitrite in water T=0°C; 0.166667 h; 2: With ammonium hydroxide in water pH=10 - 11;
参考文献
Magnetic Resonance in Chemistry, , vol. 40, # 4 p. 300 - 302
反应条件
1: 2: With thionyl chloride
参考文献
MEMORY PHARMACEUTICALS CORPORATION
Patent: WO2004/14911 A1, 2004 ;
Location in patent: Page 43 ;
WO 2004/014911 A1
反应条件
hydrogenchloride; sodium nitrite in water
参考文献
Gupte, Rajan; Rohit, Chaturvedi; Pravin, Baviskar
Patent: US2011/230658 A1, 2011 ;
反应条件
nucleoside-phosphorus ylase
参考文献
Flaks et al.
Journal of Biological Chemistry, 1957 , vol. 228, p. 201,207
反应条件
1: 5-amino-4-imidazolecarboxamide With hydrogenchloride; sodium nitrite in water T=0°C; 2: 1-chloro-2-isocyanato-ethane in water; ethyl acetate T=30°C; 48 h;
参考文献
Jean-Claude, Bertrand
Patent: US2012/283280 A1, 2012 ;
Location in patent: Page/Page column 6-7 ;
参考文献
Shaw
Journal of Biological Chemistry, 1950 , vol. 185, p. 439,442
反应条件
1H-imidazole in N,N-dimethyl-formamide T=80°C; 3 h;
参考文献
Matsumoto, Hiroatsu; Ikeda, Kazuyoshi; Nagata, Nobuyuki; Takayanagi, Hiroaki; Mizuno, Yoshihisa; Tanaka, Motohiro; Sasaki, Takuma
Journal of Medicinal Chemistry, 1999 , vol. 42, # 9 p. 1661 - 1666
参考文献
Chern, Ji-Wang; Lee, Horng-Yuh; Huang, Min; Shish, Fang-Jy
Tetrahedron Letters, 1987 , vol. 28, # 19 p. 2151 - 2154
