5-氨基-4-咪唑甲酰胺合成路线 (共 23 条)
反应条件
1: With methanesulfonic acid in ethanol 288 h; Heating / reflux; 2: With sodium hydroxide; water in water T=0°C; pH=6;
参考文献
McArthur, Silvia Gatti; Goetschi, Erwin; Wichmann, Juergen; Woltering, Thomas Johannes
Patent: US2007/72879 A1, 2007 ;
Location in patent: Page/Page column 18 ;
US 20070072879 A1
反应条件
sulfuric acid T=120°C; 24 h; Sealed tube;
参考文献
SIRTRIS PHARMACEUTICALS, INC.; CASAUBON, Rebecca, L.; NARAYAN, Radha; OALMANN, Christopher; VU, Chi, B.
Patent: WO2013/59587 A1, 2013 ;
Location in patent: Page/Page column 152 ;
反应条件
in acetic acid
4 h; Heating;
参考文献
Mokrushin, V. S.; Pospelova, T. A.; Bakulev, V. A.; Golovina, E. F.; Nikolaeva, S. L.; Pushkareva, Z. V.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1984 , vol. 20, # 2 p. 204 - 209
Khimiya Geterotsiklicheskikh Soedinenii, 1984 , vol. 20, # 2 p. 247 - 252