反应条件
1.1: 68 percent / NEt3 / diethyl ether; toluene / 4 h / 70 °C
2.1: LDA / hexane; tetrahydrofuran / 1.5 h / -78 °C
2.2: 70 percent / hexane; tetrahydrofuran / 2 h / -78 °C
3.1: 85 percent / PPTS / methanol / 14 h / 20 °C
4.1: 92 percent / 2,6-lutidine / CH2Cl2 / 3.75 h / -78 - 20 °C
5.1: 78 percent / camphorsulfonic acid / CH2Cl2; methanol / 4 h / 0 °C
6.1: 83 percent / PDC / dimethylformamide / 36 h / 20 °C
7.1: 81 percent / DCC; DMAP / CH2Cl2 / 14 h / 20 °C
8.1: 80 percent / CH2Cl2 / [Mo{(t-Bu)(3,5-dimethylphenyl)N}3] / toluene / 8 h / 80 °C
9.1: 99 percent / quinoline; H2 / Lindlar catalyst / hexane; CH2Cl2 / 8 h / 20 °C
10.1: 79 percent / aq. HF / acetonitrile; diethyl ether / 8 h / 20 °C
View Scheme
