4-溴苯并[b]噻吩-2-羧酸甲酯合成路线 (共 4 条)
反应条件
potassium carbonate in N,N-dimethyl-formamide
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 12 p. 2998 - 3001
反应条件
1.1: LDA / tetrahydrofuran / -78 °C 1.2: tetrahydrofuran 2.1: K2CO3 / dimethylformamide View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 12 p. 2998 - 3001
反应条件
tetrakis(triphenylphosphine) palladium(0); potassium carbonate in N,N-dimethyl-formamide Suzuki reaction; Heating;
参考文献
Lee, Sunkyung; Lee, Hyunsuk; Kyu, Yang Yi; Byung, Ho Lee; Yoo, Sung-Eun; Lee, Kyunghee; Nam, Sook Cho
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 12 p. 2998 - 3001
反应条件
hydrogenchloride; sodium hydroxide in methanol; water
参考文献
Kissei Pharmaceutical Co., Ltd.
Patent: EP1724277 A1, 2006 ;
Location in patent: Page/Page column 28-29 ;