1: (S)-(+)-2-phenylglycine methyl ester hydrochloride With sodium hydrogencarbonate in water Cooling; 2: acetic anhydride in water 0.25 h; Cooling with ice;

hydrogen; norborna-2,5-diene(S,S-1,2-bis(2,5-diethylphospholanyl)benzene)rhodium(I) tetrafluoroborate in ethanol T=26°C; P=2250.18 Torr; Kinetics; Further Variations:Catalysts;

anhydrous magnesium perchlorate; 1-PhCH2-3-N-[(1S,2R)-2-HOCH2C6H10]NHCO-1,4-dihydropyridine in acetonitrile T=20°C; Reduction; 6.5 h; Title compound not separated from byproducts;

Carica papaya lipase in hexane T=45°C; Resolution of racemateEnzymatic reaction;

1: methyl phenylglycinate hydrochloride With triethylamine in tetrahydrofuran T=20°C; 2: (1S,1'S)-1,1'-(1-acetyl-1H-1,2,4-triazole-3,5-diyl)-bis(ethane-1,1-diyl) diacetate in tetrahydrofuran T=25°C; enantioselective reaction;