羟基-二苯基-乙酸 1-甲基-哌啶-4-基酯合成路线 （共 19 条）
反应条件
hydrogenchloride 100 h; Heatinghydrolytic degradation in 0.1 N HCl, H2O, 0.1 N NaOH/n-propanol (3:1) and without solvens (90 deg C, 50 d), further times;
参考文献
Gober; Dressler; Franke; Alder
Pharmazie, 1986 , vol. 41, # 12 p. 840 - 842
反应条件
1H-imidazole; hydrogenchloride; dihydrogen peroxide; MnTPFPS4PCl in water T=20°C; 24 h; var. of pH, solvent, catalyst; Product distribution;
参考文献
Pharmazie, , vol. 51, # 10 p. 745 - 747
反应条件
hydrogenchloride 100 h; Heatinghydrolytic degradation in 0.1 N HCl, H2O, 0.1 N NaOH/n-propanol (3:1) and without solvens (90 deg C, 50 d), further times;
参考文献
Pharmazie, , vol. 41, # 12 p. 840 - 842
反应条件
hydrogenchloride 100 h; Heatinghydrolytic degradation in 0.1 N HCl, H2O, 0.1 N NaOH/n-propanol (3:1) and without solvens (90 deg C, 50 d), further times;
参考文献
Gober; Dressler; Franke; Alder
Pharmazie, 1986 , vol. 41, # 12 p. 840 - 842
反应条件
1H-imidazole; dihydrogen peroxide; (5,10,15,20-tetrakis(pentafluorophenyl)porphyrin)MnCl in methanol; dichloromethane T=20°C; 24 h; Further byproducts given;
参考文献
Froehlich; Pietzyk; Smolinka; Goeber
Pharmazie, 1996 , vol. 51, # 10 p. 745 - 747
反应条件
1H-imidazole; dihydrogen peroxide; (5,10,15,20-tetrakis(pentafluorophenyl)porphyrin)MnCl in methanol; dichloromethane T=20°C; 24 h; Further byproducts given;
参考文献
Froehlich; Pietzyk; Smolinka; Goeber
Pharmazie, 1996 , vol. 51, # 10 p. 745 - 747
反应条件
MnTPFPPCl in methanol; dichloromethane T=20°C; 24 h; Further byproducts given;
参考文献
Frohlich; Pietzyk; Gober
Pharmazie, 1995 , vol. 50, # 11 p. 736 - 740
反应条件
1: diethyl ether
2: methanol; silver bromide
View Scheme
参考文献
Coan et al.
Journal of the American Chemical Society, 1956 , vol. 78, p. 3701
参考文献
Coan et al.
Journal of the American Chemical Society, 1956 , vol. 78, p. 3701
