2-苯基-1,3-噻唑-4-羰酰氯合成路线 （共 7 条）
参考文献
Journal of the American Chemical Society, , vol. 65, p. 1667,1669
反应条件
1: ethanol / 75 °C 2: aq. KOH / 50 °C 3: oxalyl chloride; DMF / CH2Cl2 / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 20 p. 3491 - 3495
反应条件
1: aqueous NaOH 2: CrO3; H2SO4 3: SOCl2 View Scheme
参考文献
Journal of the American Chemical Society, , vol. 65, p. 1667,1669
反应条件
1: CrO3; H2SO4 2: SOCl2 View Scheme
参考文献
Journal of the American Chemical Society, , vol. 65, p. 1667,1669
反应条件
1: aq. KOH / 50 °C 2: oxalyl chloride; DMF / CH2Cl2 / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 20 p. 3491 - 3495
反应条件
1: triethylamine / dichloromethane / 1 h / 20 °C / |Cooling with ice 2: tetrahydrofuran; anhydrous butyl ether / 0.53 h / 0 °C View Scheme
参考文献
BRISTOL-MYERS SQUIBB COMPANY; UNIVERSITÉ DE MONTRÉAL; BANVILLE, Jacques; RÉMILLARD, Roger; RUEDIGER, Edward H.; DEON, Daniel H.; GAGNON, Marc; DUBÉ, Laurence; GUY, Julia; PRIESTLEY, Eldon Scott; POSY, Shoshana L.; MAXWELL, Brad D.; WONG, Pancras C.
Patent: WO2013/163279 A1, 2013 ;
反应条件
sodium azide in tetrahydrofuran
T=40°C;
参考文献
Larsen, Scott D.; Stachew, Carl F.; Clare, Paula M.; Cubbage, Jerry W.; Leach, Karen L.
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 20 p. 3491 - 3495
