N-苄基哌啶酮合成路线

参考文献

Conway, Richard J.; Valant, Celine; Christopoulos, Arthur; Robertson, Alan D.; Capuano, Ben; Crosby, Ian T.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 7 p. 2560 - 2564

3612-20-2N-苄基哌啶酮+

352-13-64-氟苯基溴化镁

163631-02-51-苄基-4-(4-氟苯基)哌啶-4-醇

参考文献

Synaptic Pharmaceutical Corporation
Patent: US6159990 A1, 2000 ;
US 6159990 A

3612-20-2N-苄基哌啶酮+

24424-99-5二碳酸二叔丁酯+

74-89-5甲胺

139062-92-3(1-苄基哌啶-4-基)(甲基)氨基甲酸叔丁酯

参考文献

sanofi-aventis
Patent: US2008/269170 A1, 2008 ;
Location in patent: Page/Page column 21 ;

3612-20-2N-苄基哌啶酮

139062-92-3(1-苄基哌啶-4-基)(甲基)氨基甲酸叔丁酯

参考文献

GRUENENTHAL GmbH
Patent: US2012/71461 A1, 2012 ;

3612-20-2N-苄基哌啶酮+

18620-02-5

16332-18-6

参考文献

Wenzel, Barbara; Sorger, Dietlind; Heinitz, Katrin; Scheunemann, Matthias; Schliebs, Reinhard; Steinbach, Joerg; Sabri, Osama
European Journal of Medicinal Chemistry, 2005 , vol. 40, # 12 p. 1197 - 1205

3612-20-2N-苄基哌啶酮+

106-37-6对二溴苯

16332-18-6

参考文献

Vieira, Eric; Binggeli, Alfred; Breu, Volker; Bur, Daniel; Fischli, Walter; Gueller, Rolf; Hirth, Georges; Maerki, Hans Peter; Mueller, Marcel; Oefner, Christian; Scalone, Michelangelo; Stadler, Heinz; Wilhelm, Maurice; Wostl, Wolfgang
Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 10 p. 1397 - 1402

773837-37-9+

3612-20-2N-苄基哌啶酮

136624-42-54-氨基-1-苄基哌啶-4-甲腈

参考文献

Chaturvedula, Prasad V.; Pin, Sokhom; Tholady, George; Conway, Charlie M.; MacOr, John E.; Dubowchik, Gene M.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 14 p. 4719 - 4722

3612-20-2N-苄基哌啶酮+

7677-24-9三甲基氰硅烷

136624-42-54-氨基-1-苄基哌啶-4-甲腈

参考文献

SCHERING CORPORATION
Patent: EP1032561 B1, 2004 ;
Location in patent: Page 17 ;
EP 1032561 B1

3612-20-2N-苄基哌啶酮+

151-50-8氰化钾

136624-42-54-氨基-1-苄基哌啶-4-甲腈

参考文献

Metwally, Kamel A.; Dukat, Malgorzata; Egan, Christina T.; Smith, Carol; DuPre, Ann; Gauthier, Colleen B.; Herrick-Davis, Katharine; Teitler, Milt; Glennon, Richard A.
Journal of Medicinal Chemistry, 1998 , vol. 41, # 25 p. 5084 - 5093

3612-20-2N-苄基哌啶酮+

151-50-8氰化钾

6094-60-61苄基-4-氰基-4-羟基哌啶+

136624-42-54-氨基-1-苄基哌啶-4-甲腈

参考文献

Cumbre Inc.
Patent: US2005/277633 A1, 2005 ;
Location in patent: Page/Page column 17 ;
US 20050277633 A1