2-(2,6-二氟-3-硝基苯基)乙酸合成路线 （共 3 条）
反应条件
nitric acid in methanol T=-10°C; 0.25 h;
参考文献
Parlow, John J.; Stevens, Anna M.; Stegeman, Roderick A.; Stallings, William C.; Kurumbail, Ravi G.; South, Michael S.
Journal of Medicinal Chemistry, 2003 , vol. 46, # 20 p. 4297 - 4312
反应条件
1: oxalyl chloride; DMF / CH2Cl2 / 20 °C 2: 5.47 g / pyridine / CH2Cl2 / 20 °C 3: 68 percent / Fe; glacial acetic acid / 80 °C View Scheme
参考文献
Parlow, John J.; Stevens, Anna M.; Stegeman, Roderick A.; Stallings, William C.; Kurumbail, Ravi G.; South, Michael S.
Journal of Medicinal Chemistry, 2003 , vol. 46, # 20 p. 4297 - 4312
反应条件
1: oxalyl chloride; DMF / CH2Cl2 / 20 °C 2: 5.47 g / pyridine / CH2Cl2 / 20 °C View Scheme
参考文献
Parlow, John J.; Stevens, Anna M.; Stegeman, Roderick A.; Stallings, William C.; Kurumbail, Ravi G.; South, Michael S.
Journal of Medicinal Chemistry, 2003 , vol. 46, # 20 p. 4297 - 4312
