1-氨基-1,3-二氢-2H-吲哚-2-酮合成路线 (共 9 条)
反应条件
sulfuric acid in ethanol 2 h; Heating; Yield given;
参考文献
Zey, Robert L.
Journal of Heterocyclic Chemistry, 1987 , vol. 24, p. 1261 - 1263
反应条件
sulfuric acid; zinc in dichloromethane 5 h; Ambient temperaturealso with 15N-labelled compounds; Mechanism;
参考文献
Williams, Michael T.
Journal of Chemical Research, Miniprint, 1986 , # 4 p. 1185 - 1194
反应条件
bei rascher Destillation;
参考文献
Neber
Chemische Berichte, 1922 , vol. 55, p. 839
参考文献
Winters et al.
Journal of Heterocyclic Chemistry, 1974 , vol. 11, p. 997,998,1000
反应条件
lead(IV) acetate in dichloromethane 5 h; Ambient temperaturealso with 15N-labelled compounds; Mechanism;
参考文献
Williams, Michael T.
Journal of Chemical Research, Miniprint, 1986 , # 4 p. 1185 - 1194
反应条件
isopentyl nitrite in dichloromethane 5 h; Ambient temperaturealso with 15N-labelled compounds; Mechanism;
参考文献
Williams, Michael T.
Journal of Chemical Research, Miniprint, 1986 , # 4 p. 1185 - 1194
参考文献
Neber
Chemische Berichte, 1922 , vol. 55, p. 839
反应条件
1: 82 percent / p.toluenesulfonic acid / benzene / 4 h / Heating
2: 47 percent / Na / ethanol / 0.5 h / Heating
3: 95 percent / NaOH / methanol / 4 h / Heating
4: 90 percent / neat (no solvent) / 1 h / 260 °C
View Scheme
参考文献
Winters; Odasso; Conti; et al.
European Journal of Medicinal Chemistry, 1984 , vol. 19, # 3 p. 215 - 218
反应条件
1: 92 percent / ethanol / Heating
2: H2 / palladium on chalcoal / ethanol / 2327.2 Torr
3: 76 percent / t-butyl hypochlorite / benzene
View Scheme
参考文献
Zey, R.L.; Richter, G.; Randa, H.
Journal of Heterocyclic Chemistry, 1989 , vol. 26, p. 1437 - 1439