(3-氨基-4-氟苯基)-氨基甲酸叔丁酯合成路线 （共 4 条）
反应条件
hydrogen; palladium in methanol T=20°C;
参考文献
Kuramoto, Yasuhiro; Ohshita, Yoshihiro; Yoshida, Jiro; Yazaki, Akira; Shiro, Motoo; Koike, Tohru
Journal of Medicinal Chemistry, 2003 , vol. 46, # 10 p. 1905 - 1917
反应条件
1: 88 percent / KNO3; conc. H2SO4 / 20 °C 2: oxalyl chloride; DMF / CH2Cl2 / 20 °C 3: sodium azide / CH2Cl2; dimethylformamide / 20 °C 4: CH2Cl2; dimethylformamide / Heating 5: 47 percent / H2 / palladium black / methanol / 20 °C View Scheme
参考文献
Kuramoto, Yasuhiro; Ohshita, Yoshihiro; Yoshida, Jiro; Yazaki, Akira; Shiro, Motoo; Koike, Tohru
Journal of Medicinal Chemistry, 2003 , vol. 46, # 10 p. 1905 - 1917
反应条件
1: oxalyl chloride; DMF / CH2Cl2 / 20 °C 2: sodium azide / CH2Cl2; dimethylformamide / 20 °C 3: CH2Cl2; dimethylformamide / Heating 4: 47 percent / H2 / palladium black / methanol / 20 °C View Scheme
参考文献
Kuramoto, Yasuhiro; Ohshita, Yoshihiro; Yoshida, Jiro; Yazaki, Akira; Shiro, Motoo; Koike, Tohru
Journal of Medicinal Chemistry, 2003 , vol. 46, # 10 p. 1905 - 1917
反应条件
1: sodium azide / CH2Cl2; dimethylformamide / 20 °C 2: CH2Cl2; dimethylformamide / Heating 3: 47 percent / H2 / palladium black / methanol / 20 °C View Scheme
参考文献
Kuramoto, Yasuhiro; Ohshita, Yoshihiro; Yoshida, Jiro; Yazaki, Akira; Shiro, Motoo; Koike, Tohru
Journal of Medicinal Chemistry, 2003 , vol. 46, # 10 p. 1905 - 1917
