N-乙酰-L-苯丙氨酸甲酯合成路线 （共 84 条）
反应条件
(S,S)-Bn-nbd; tetrakis-(ethylene)-μ,μ'-dichlorodirhodium(I); water in toluene T=50°C; 48 h; Inert atmosphereSealed tube; optical yield given as percent ee;
参考文献
Tetrahedron Asymmetry, , vol. 21, # 5 p. 540 - 543
反应条件
1: mercaptoacetic acid; triethylamine / 0.08 h / 20 °C / |Ionic liquid 2: dichloromethane; water / 4 h / 20 °C / |Alkaline conditions View Scheme
参考文献
RSC Advances, , vol. 4, # 6 p. 2678 - 2686
反应条件
Rhizomucor miehei lipase in acetonitrile T=30°C; 24 h; Inert atmosphereEnzymatic reaction; SolventTimeTemperature; enantioselective reaction;
参考文献
Tetrahedron, , vol. 70, # 13 p. 2264 - 2271
反应条件
1: BF3*Et2O; calcium carbonate / methanol / Heating 2: CH2Cl2 / 20 °C 3: subtilisin Carlsberg type VIII / H2O; liquid carbon dioxide / 47 °C / 85329.4 Torr View Scheme
参考文献
Australian Journal of Chemistry, , vol. 55, # 4 p. 259 - 262
反应条件
1: CH2Cl2 / 20 °C 2: subtilisin Carlsberg type VIII / H2O; liquid carbon dioxide / 47 °C / 85329.4 Torr View Scheme
参考文献
Australian Journal of Chemistry, , vol. 55, # 4 p. 259 - 262
反应条件
1: BF3*OEt2, molecular sieves / CH2Cl2 / 20 h / Ambient temperature 2: Et3N / tetrahydrofuran / 1.5 h / Heating View Scheme
参考文献
Synthetic Communications, , vol. 27, # 11 p. 1819 - 1825
反应条件
1: potassium carbonate / acetone / 6 h / |Inert atmosphere; |Schlenk technique; |Reflux 2: (R)-1-(3,5-dioxa-4-phosphacyclohepta[2,1-a:3,4-a']dinaphthalen-4-yl)-4-pentafluorophenylmethylpiperazine; bis(1,5-cyclooctadiene)-rhodium(I) tetrafluoroborate; hydrogen / toluene / 1 h / 20 °C / 7500.75 Torr / |Inert atmosphere; |Schlenk technique View Scheme
参考文献
Chemistry - A European Journal, , vol. 19, # 7 p. 2405 - 2415
反应条件
Rhizomucor miehei lipase in tert-butyl methyl ether T=30°C; 8 h; Inert atmosphereEnzymatic reaction; Solvent; enantioselective reaction;
参考文献
Tetrahedron, , vol. 70, # 13 p. 2264 - 2271
反应条件
in ethyl acetate Esterification;
参考文献
Helvetica Chimica Acta, , vol. 83, # 1 p. 258 - 277
反应条件
subtilisin A; water T=40°C; Ionic liquidEnzymatic reaction;
参考文献
Chemical Communications, , vol. 46, # 5 p. 749 - 751
