N-乙酰-L-苯丙氨酸甲酯合成路线 （共 84 条）
反应条件
1: pyridine / dichloromethane / 1 h / 20 °C 2: dichloromethane / 20 °C View Scheme
参考文献
Chemical Science, , vol. 4, # 3 p. 970 - 976
反应条件
(S)-1-phenyl-ethylamine; hydrogen; palladium dichloride
参考文献
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), , vol. 36, # 10 p. 2118 - 2123
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, , # 10 p. 2286 - 2292
反应条件
in hexane Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Chemical Communications, , # 18 p. 1713 - 1714
反应条件
in dichloromethane T=20°C;
参考文献
Chemical Science, , vol. 4, # 3 p. 970 - 976
反应条件
N,N'-dimethyl-N,N'-propyleneurea T=-20°C; 24 h; Title compound not separated from byproducts;
参考文献
Angewandte Chemie - International Edition, , vol. 43, # 25 p. 3314 - 3317
反应条件
1: pyridine; 4-(N,N-dimethlyamino)pyridine / dichloromethane / 4 h / 20 °C 2: Rhizomucor miehei lipase / acetonitrile / 24 h / 30 °C / |Inert atmosphere; |Enzymatic reaction View Scheme
参考文献
Tetrahedron, , vol. 70, # 13 p. 2264 - 2271
反应条件
1: hydrogenchloride; water / 30 h / |Reflux 2: hydrogenchloride / water / 1 h / |Reflux 3: pyridine; 4-(N,N-dimethlyamino)pyridine / dichloromethane / 4 h / 20 °C 4: Rhizomucor miehei lipase / acetonitrile / 24 h / 30 °C / |Inert atmosphere; |Enzymatic reaction View Scheme
参考文献
Tetrahedron, , vol. 70, # 13 p. 2264 - 2271
反应条件
1: potassium carbonate; (benzyl)-tri-(butyl)-ammonium chloride / toluene / 5 h / 70 °C 2: hydrogenchloride; water / 30 h / |Reflux 3: hydrogenchloride / water / 1 h / |Reflux 4: pyridine; 4-(N,N-dimethlyamino)pyridine / dichloromethane / 4 h / 20 °C 5: Rhizomucor miehei lipase / acetonitrile / 24 h / 30 °C / |Inert atmosphere; |Enzymatic reaction View Scheme
参考文献
Tetrahedron, , vol. 70, # 13 p. 2264 - 2271
反应条件
1: potassium carbonate; (benzyl)-tri-(butyl)-ammonium chloride / toluene / 5 h / 70 °C 2: hydrogenchloride; water / 30 h / |Reflux 3: hydrogenchloride / water / 1 h / |Reflux 4: pyridine; 4-(N,N-dimethlyamino)pyridine / dichloromethane / 4 h / 20 °C 5: Rhizomucor miehei lipase / acetonitrile / 24 h / 30 °C / |Inert atmosphere; |Enzymatic reaction View Scheme
参考文献
Tetrahedron, , vol. 70, # 13 p. 2264 - 2271
反应条件
1: hydrogenchloride / water / 1 h / |Reflux 2: pyridine; 4-(N,N-dimethlyamino)pyridine / dichloromethane / 4 h / 20 °C 3: Rhizomucor miehei lipase / acetonitrile / 24 h / 30 °C / |Inert atmosphere; |Enzymatic reaction View Scheme
参考文献
Tetrahedron, , vol. 70, # 13 p. 2264 - 2271
